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View Structure Prediction Details

Protein: CE22211
Organism: Caenorhabditis elegans
Length: 390 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE22211.

Description E-value Query
Range		 Subject
Range
gi|39589916, gi|... - gi|39589916|emb|CAE60914.1| Hypothetical protein CBG04631 [Caenorhabditis briggsae], gi|187035418|em...
gi|157765166 - gi|157765166|ref|XP_001674926.1| Hypothetical protein CBG04631 [Caenorhabditis briggsae AF16]
 349.0 [0..12] [390..1]

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Predicted Domain #1
Region A:
Residues: [1-85] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELDSVKQQQ QQNACCEYIL PIKKRRCKML VKKGNRFCGE HSIHDQNNTD RMVCPNDGKH  60
   61 TILKADLEIH LTRCNSRIRD AEYIK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [86-286] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDANSIRGET KRTDKIDRRA TEDEICTTVH KIWKCYETDV MDRLIVEQQR NELVEQNIAQ  60
   61 NSDLNNTKKK QLYQISSILG HIESTGLLPT CSKSCMFELG AGKGQLAYWI SKAAPNGNYI 120
  121 LMDRSGSRNK FDTAAFRENP NLSMKRFRCS IEHMDLSKID ELKNSEKILA ICKHFCGSAT 180
  181 DAGIRSLMNS GLQFNAALLI P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 1r18A
Description: Drosophila protein isoaspartyl methyltransferase with S-adenosyl-L-homocysteine
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
methyltransferase activity 4.15445027778357 bayes_pls_golite062009
N-methyltransferase activity 4.07806017452628 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 4.07153733729662 bayes_pls_golite062009
protein methyltransferase activity 3.92746815303714 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.39429041855776 bayes_pls_golite062009
RNA methyltransferase activity 3.07428840534971 bayes_pls_golite062009
histone methyltransferase activity 2.99461585647365 bayes_pls_golite062009
transferase activity 2.926540904444 bayes_pls_golite062009
tRNA methyltransferase activity 2.5931020126592 bayes_pls_golite062009
DNA-methyltransferase activity 2.43145108778901 bayes_pls_golite062009
arginine N-methyltransferase activity 2.41876112831625 bayes_pls_golite062009
protein-arginine N-methyltransferase activity 2.41876112831625 bayes_pls_golite062009
rRNA methyltransferase activity 2.29640050660273 bayes_pls_golite062009
histone-arginine N-methyltransferase activity 2.04296107639729 bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity 1.88889414729709 bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity 1.88889414729709 bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity 1.66871163498737 bayes_pls_golite062009
tRNA (adenine-N1-)-methyltransferase activity 1.29759910099835 bayes_pls_golite062009
tRNA (adenine)-methyltransferase activity 1.29759910099835 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific) 1.1103522853299 bayes_pls_golite062009
transcription regulator activity 0.914549843668268 bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity 0.89325812193225 bayes_pls_golite062009
DNA binding 0.86027591375666 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 0.720972789045101 bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity 0.703178429468566 bayes_pls_golite062009
nucleic acid binding 0.616949327277483 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 0.533090627724779 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 0.455449410561251 bayes_pls_golite062009
RNA binding 0.417524996559564 bayes_pls_golite062009
binding 0.383237930789959 bayes_pls_golite062009
protein-arginine omega-N symmetric methyltransferase activity 0.364369105571521 bayes_pls_golite062009
tRNA (guanine) methyltransferase activity 0.203168546434167 bayes_pls_golite062009
rRNA (uridine) methyltransferase activity 0.0858581024725429 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [287-390] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CCHHKSRFAE YGGHDFLEKW EMNDEASFAA LRYIASFATN GAVDTEATEG WKSIHPPLEL  60
   61 GRRAKAILEI GRAIWLESVG FKTRVVEYVP PEVSPENLLI LALK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.09691
Match: 2p35A
Description: No description for 2p35A was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle