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View Structure Prediction Details

Protein: CE22211
Organism: Caenorhabditis elegans
Length: 390 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE22211.

Description E-value Query
Range		 Subject
Range
gi|39589916, gi|... - gi|39589916|emb|CAE60914.1| Hypothetical protein CBG04631 [Caenorhabditis briggsae], gi|187035418|em...
gi|157765166 - gi|157765166|ref|XP_001674926.1| Hypothetical protein CBG04631 [Caenorhabditis briggsae AF16]
 349.0 [0..12] [390..1]

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Predicted Domain #1
Region A:
Residues: [1-85] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELDSVKQQQ QQNACCEYIL PIKKRRCKML VKKGNRFCGE HSIHDQNNTD RMVCPNDGKH  60
   61 TILKADLEIH LTRCNSRIRD AEYIK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [86-286] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDANSIRGET KRTDKIDRRA TEDEICTTVH KIWKCYETDV MDRLIVEQQR NELVEQNIAQ  60
   61 NSDLNNTKKK QLYQISSILG HIESTGLLPT CSKSCMFELG AGKGQLAYWI SKAAPNGNYI 120
  121 LMDRSGSRNK FDTAAFRENP NLSMKRFRCS IEHMDLSKID ELKNSEKILA ICKHFCGSAT 180
  181 DAGIRSLMNS GLQFNAALLI P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 1r18A
Description: Drosophila protein isoaspartyl methyltransferase with S-adenosyl-L-homocysteine
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
methyltransferase activity 4.15445027778357 bayes_pls_golite062009
N-methyltransferase activity 4.07806017452628 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 4.07153733729662 bayes_pls_golite062009
protein methyltransferase activity 3.92746815303714 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.39429041855776 bayes_pls_golite062009
RNA methyltransferase activity 3.07428840534971 bayes_pls_golite062009
histone methyltransferase activity 2.99461585647365 bayes_pls_golite062009
transferase activity 2.926540904444 bayes_pls_golite062009
tRNA methyltransferase activity 2.5931020126592 bayes_pls_golite062009
DNA-methyltransferase activity 2.43145108778901 bayes_pls_golite062009
arginine N-methyltransferase activity 2.41876112831625 bayes_pls_golite062009
protein-arginine N-methyltransferase activity 2.41876112831625 bayes_pls_golite062009
rRNA methyltransferase activity 2.29640050660273 bayes_pls_golite062009
histone-arginine N-methyltransferase activity 2.04296107639729 bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity 1.88889414729709 bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity 1.88889414729709 bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity 1.66871163498737 bayes_pls_golite062009
tRNA (adenine-N1-)-methyltransferase activity 1.29759910099835 bayes_pls_golite062009
tRNA (adenine)-methyltransferase activity 1.29759910099835 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific) 1.1103522853299 bayes_pls_golite062009
transcription regulator activity 0.914549843668268 bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity 0.89325812193225 bayes_pls_golite062009
DNA binding 0.86027591375666 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 0.720972789045101 bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity 0.703178429468566 bayes_pls_golite062009
nucleic acid binding 0.616949327277483 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 0.533090627724779 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 0.455449410561251 bayes_pls_golite062009
RNA binding 0.417524996559564 bayes_pls_golite062009
binding 0.383237930789959 bayes_pls_golite062009
protein-arginine omega-N symmetric methyltransferase activity 0.364369105571521 bayes_pls_golite062009
tRNA (guanine) methyltransferase activity 0.203168546434167 bayes_pls_golite062009
rRNA (uridine) methyltransferase activity 0.0858581024725429 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [287-390] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CCHHKSRFAE YGGHDFLEKW EMNDEASFAA LRYIASFATN GAVDTEATEG WKSIHPPLEL  60
   61 GRRAKAILEI GRAIWLESVG FKTRVVEYVP PEVSPENLLI LALK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.09691
Match: 2p35A
Description: No description for 2p35A was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle