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View Structure Prediction Details

Protein: CE22129
Organism: Caenorhabditis elegans
Length: 377 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE22129.

Description E-value Query
Range
Subject
Range
gi|157104385, gi... - gi|157104385|ref|XP_001648384.1| diphosphomevalonate decarboxylase [Aedes aegypti], gi|108880368|gb|...
359.0 [0..9] [377..1]

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Predicted Domain #1
Region A:
Residues: [1-377]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQDDGAAEA EATVRVPMNI ALVKYWGKRD DLLILPLNDS ISLTVDRLTA ETTIRMVPGV  60
   61 GKHTVEINGK SVELSSNKRY QTVFDEALRL QRKRKEAEAS SADSNGNDPP PIFYHFHVTS 120
  121 TTNFPVAAGL ASSAAGFAAI ALAIQRILRL DDSQANRLAR IGSGSACRSM YGGLVHWRKG 180
  181 EMDDGSDCLA VRTEAAANWE DLYCIILVFD DGRKKVGSSE GMRRSRETSQ LLKHRIESIV 240
  241 PQRIQQIQEA YTSRNFEQLA RVIMADSNQF HAVCMDSTPP IRYLNEASWQ LIDTVEEFNI 300
  301 GGIRAAYTFD AGPNACVIVQ KENASQFLKA VLQTIQVPSE DLQVIGKELA EQFDVPAEPT 360
  361 TKCSKLIMSP MGGGPQE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.69897
Match: 1fi4A
Description: Mevalonate 5-diphosphate decarboxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
diphosphomevalonate decarboxylase activity 2.34245588421319 bayes_pls_golite062009
binding 1.48300512137561 bayes_pls_golite062009
catalytic activity 0.836142537655721 bayes_pls_golite062009
structural constituent of ribosome 0.66774567862554 bayes_pls_golite062009
carbohydrate kinase activity 0.49664490095304 bayes_pls_golite062009
structural molecule activity 0.40691892506083 bayes_pls_golite062009
nucleic acid binding 0.369771518688522 bayes_pls_golite062009
protein binding 0.214066724623027 bayes_pls_golite062009
transcription regulator activity 0.212099606954236 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle