YRC Public Data Repository - Protein Structure Prediction

Protein:	CE21481
Organism:	Caenorhabditis elegans
Length:	297 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE21481.

Description	E-value	Query Range	Subject Range
gi\|20807045, gi\|... - gi\|20807045\|ref\|NP_622216.1\| 3-hydroxybutyryl-CoA dehydratase [Thermoanaerobacter tengcongensis MB4]... gi\|20807045 - gi\|20807045\|ref\|NP_622216.1\| enoyl-CoA hydratase [Thermoanaerobacter tengcongensis MB4]	277.0	[0..24]	[296..2]
gi\|28204455, gi\|... - gi\|28212012\|ref\|NP_782956.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium tetani E88], gi\|28204455\|...	269.0	[0..22]	[296..1]
gi\|241218800, gi... - gi\|241769557\|ref\|ZP_04766976.1\| Enoyl-CoA hydratase/isomerase [Sulfolobus solfataricus 98/2], gi\|241... gi\|25291790 - pir\|\|A90436 enoyl CoA hydratase (paaF-7) [imported] - Sulfolobus solfataricus gi\|13815932, gi\|... - gi\|15899349\|ref\|NP_343954.1\| enoyl CoA hydratase (paaF-7) [Sulfolobus solfataricus P2], gi\|13815932\|...	267.0	[0..24]	[296..8]
gi\|70606884, gi\|... - gi\|70606884\|ref\|YP_255754.1\| 3-hydroxybutyryl-CoA dehydrogenase [Sulfolobus acidocaldarius DSM 639],...	266.0	[0..23]	[296..406]
gi\|18145966, gi\|... - gi\|18311283\|ref\|NP_563217.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens str. 13], gi\|... gi\|110673862, gi... - gi\|110799215\|ref\|YP_696975.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens ATCC 13124],... gi\|182625533, gi... - gi\|182625533\|ref\|ZP_02953304.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens D str. JGS... gi\|170715197, gi... - gi\|170715197\|gb\|EDT27379.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens CPE str. F4969...	265.0	[0..28]	[296..6]
gi\|88926146, gi\|... - gi\|88944140\|ref\|ZP_01147473.1\| putative crotonase [Desulfotomaculum reducens MI-1], gi\|88926146\|gb\|E...	265.0	[0..26]	[296..4]
gi\|110683900, gi... - gi\|110803399\|ref\|YP_699562.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens SM101], gi\|1...	264.0	[0..28]	[296..6]
gi\|77997022, gi\|... - gi\|78044907\|ref\|YP_360429.1\| 3-hydroxybutyryl-CoA dehydratase [Carboxydothermus hydrogenoformans Z-2...	264.0	[0..24]	[296..2]
gi\|15622596, gi\|... - gi\|15921809\|ref\|NP_377478.1\| 3-hydroxybutyryl-CoA dehydratase [Sulfolobus tokodaii str. 7], gi\|15622...	264.0	[0..26]	[296..14]
gi\|7428375 - pir\|\|C69370 probable enoyl-CoA hydratase (EC 4.2.1.17) fad-3 - Archaeoglobus fulgidus gi\|2649635, gi\|1... - gi\|2649635\|gb\|AAB90280.1\| enoyl-CoA hydratase (fad-3) [Archaeoglobus fulgidus DSM 4304], gi\|11498568...	262.0	[0..28]	[295..4]

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Predicted Domain #1

Region A:
Residues: [1-297]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLASRRLLPQ ISSRALSTSP ALKSSEISVK EERPYVYNVK LNRPAKLNTF TMDMWREFKK  60
   61 AIDSLADDPK CRSIIISGEG KAFCAGIDIA HGLSDILRII QDDTIEVGRK GRLVRKFIGE 120
  121 IQDCYTALER CPKPIIASIH SHCLGAGIDL ITACDIRVAS QDAIFSIREV DVGLAADIGT 180
  181 LNRIQKVVGN DSWTRDVAFT ARDFGADEAL RFGLISRIYD DRQSLLENSI DMAARIAEKS 240
  241 PIAVQGTKET LNYAREHSTD DSLNFIKTWN MSQLLSTDLL SSAMAVMNKK KATYEDV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.30103
Match:	1dciA
Description:	Dienoyl-CoA isomerase (delta3-delta2-enoyl-CoA isomerase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
long-chain-3-hydroxyacyl-CoA dehydrogenase activity	5.99914207874933	bayes_pls_golite062009
long-chain-enoyl-CoA hydratase activity	5.38361434383109	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	4.25084649365698	bayes_pls_golite062009
enoyl-CoA hydratase activity	3.92947460544831	bayes_pls_golite062009
CoA carboxylase activity	3.89913842968597	bayes_pls_golite062009
acetyl-CoA carboxylase activity	3.85567083340773	bayes_pls_golite062009
acetyl-CoA C-acyltransferase activity	3.6090947563188	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	3.4980371783229	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing C=C bonds	1.97586838275054	bayes_pls_golite062009
dodecenoyl-CoA delta-isomerase activity	1.80820904754223	bayes_pls_golite062009
catalytic activity	1.46154163027498	bayes_pls_golite062009
3-hydroxybutyryl-CoA epimerase activity	1.31614278936637	bayes_pls_golite062009
propionyl-CoA carboxylase activity	1.20853698666984	bayes_pls_golite062009
RNA binding	1.10276341044201	bayes_pls_golite062009
racemase and epimerase activity, acting on hydroxy acids and derivatives	1.08284170936757	bayes_pls_golite062009
ligase activity	0.98581896521131	bayes_pls_golite062009
binding	0.578223105269736	bayes_pls_golite062009
hydrolase activity	0.534319520590169	bayes_pls_golite062009
nucleic acid binding	0.472835473017362	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: