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View Structure Prediction Details

Protein: CE20700
Organism: Caenorhabditis elegans
Length: 555 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE20700.

Description E-value Query
Range
Subject
Range
gi|68436585 - gi|68436585|ref|XP_699134.1| PREDICTED: similar to Uridine/cytidine kinase-like 1 [Danio rerio]
439.0 [0..7] [554..46]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVAEKRDANV AASKGDANRK SVKIEDCPTY SHSSGSSVNE MVNQSGGDSE DSTSPRAAGC  60
   61 RTRRRTMSGG RAEHHLLTTK TGKKIYTKGR PPWYDKKGKS LKH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [104-330]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFVIGVCGGS ASGKTTVAEK IVERLGIPWV TILSMDSFYK VLTPEEIKAA HESRYNFDGP  60
   61 NAFDFDLLYE VLKRLREGKS VDVPVYDFNT HSRDPNSKMM YGADVLIFEG ILAFHDERIK 120
  121 NLMDMKVFVD TDGDLRLARR IVRDVTDRGR DIDGIMEQYF TFVKPAFDKY IAPCMDSADL 180
  181 IVPRGGENDV AIDMIVQNVM AQLVERGYDR NQNNRDRHDL VRDDLPD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.0
Match: 1xrjA
Description: Rapid structure determination of human uridine-cytidine kinase 2 using a conventional laboratory X-ray source and a single samarium derivative
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleobase, nucleoside, nucleotide kinase activity 3.66392587433723 bayes_pls_golite062009
nucleotide kinase activity 2.24094813695083 bayes_pls_golite062009
kinase activity 2.0779386406753 bayes_pls_golite062009
binding 2.05253348982328 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 1.96697952975573 bayes_pls_golite062009
nucleic acid binding 1.60768715809391 bayes_pls_golite062009
DNA binding 1.11699929651302 bayes_pls_golite062009
RNA helicase activity 1.02424782546779 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription regulator activity 0.989226939888218 bayes_pls_golite062009
RNA-dependent ATPase activity 0.95986988363392 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.94128341275411 bayes_pls_golite062009
hydrolase activity 0.533811513387322 bayes_pls_golite062009
adenylate kinase activity 0.447752711852745 bayes_pls_golite062009
protein binding 0.193768631623192 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009
transcription factor activity 0.0434163635422169 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [331-555]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CLPENLFILK ETPQVKGLVT FVRDRETSRD NHIFYSDRLM RILIEECMNH MPYKDVEIEM  60
   61 AGGRKTIGKR KDAQICGLPI MRAGECMETA LRSIVKDCVI GKILIQTNET TFDPELHYIR 120
  121 LPPHITRYKV IIMDATVTTG SAAMMAIRVL LDHDVKEEDI FVASLLMGQQ GAHALAYAFP 180
  181 KVKLITTAMD HQMTENCYLI PGMGNFGDRY YGTGLEQDMD EPFDM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.30103
Match: 1bd3D
Description: Uracil PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
uracil phosphoribosyltransferase activity 3.97944228585882 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 3.91023158228049 bayes_pls_golite062009
adenine phosphoribosyltransferase activity 3.07502596276449 bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity 2.97347277288245 bayes_pls_golite062009
transferase activity 2.73727660668741 bayes_pls_golite062009
transferase activity, transferring pentosyl groups 2.53679639481311 bayes_pls_golite062009
catalytic activity 2.30431811394775 bayes_pls_golite062009
nucleobase binding 1.70525606708275 bayes_pls_golite062009
purine binding 1.24786927434743 bayes_pls_golite062009
transcription regulator activity 1.09798789282825 bayes_pls_golite062009
nucleic acid binding 1.07284130528063 bayes_pls_golite062009
ribose phosphate diphosphokinase activity 0.947697983706416 bayes_pls_golite062009
DNA binding 0.854593555814443 bayes_pls_golite062009
diphosphotransferase activity 0.749909396904601 bayes_pls_golite062009
binding 0.691442295634288 bayes_pls_golite062009
amidophosphoribosyltransferase activity 0.360901350940423 bayes_pls_golite062009
transcription factor activity 0.339219342075596 bayes_pls_golite062009
orotate phosphoribosyltransferase activity 0.148898393751978 bayes_pls_golite062009

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