YRC Public Data Repository - Protein Structure Prediction

Protein:	exos-4.1
Organism:	Caenorhabditis elegans
Length:	240 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for exos-4.1.

Description	E-value	Query Range	Subject Range
PNP_CARHZ - Polyribonucleotide nucleotidyltransferase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 ...	282.0	[0..2]	[238..318]
PNP_RALSO - Polyribonucleotide nucleotidyltransferase OS=Ralstonia solanacearum GN=pnp PE=3 SV=1 PNP_RALSO - Polyribonucleotide nucleotidyltransferase OS=Ralstonia solanacearum (strain GMI1000) GN=pnp PE=3 SV=...	276.0	[0..3]	[238..308]
gi\|89350148, gi\|... - gi\|89361251\|ref\|ZP_01199067.1\| RNA binding S1:KH [Xanthobacter autotrophicus Py2], gi\|89350148\|gb\|EA...	274.0	[0..4]	[239..365]
gi\|83727042, gi\|... - gi\|83746292\|ref\|ZP_00943345.1\| Polyribonucleotide nucleotidyltransferase [Ralstonia solanacearum UW5...	273.0	[0..3]	[238..308]
gi\|167580418 - gi\|167580418\|ref\|ZP_02373292.1\| polynucleotide phosphorylase/polyadenylase [Burkholderia thailandens... PNP_BURTA - Polyribonucleotide nucleotidyltransferase OS=Burkholderia thailandensis (strain E264 / ATCC 700388 /...	272.0	[0..3]	[238..315]
PNP_BORA1 - Polyribonucleotide nucleotidyltransferase OS=Bordetella avium (strain 197N) GN=pnp PE=3 SV=1	272.0	[0..2]	[238..312]
PNP_GEOKA - Polyribonucleotide nucleotidyltransferase OS=Geobacillus kaustophilus GN=pnp PE=3 SV=1 PNP_GEOKA - Polyribonucleotide nucleotidyltransferase OS=Geobacillus kaustophilus (strain HTA426) GN=pnp PE=3 SV...	272.0	[0..3]	[238..309]
gi\|167918256 - gi\|167918256\|ref\|ZP_02505347.1\| polynucleotide phosphorylase/polyadenylase [Burkholderia pseudomalle... gi\|217419798, gi... - gi\|217419798\|ref\|ZP_03451304.1\| polyribonucleotide nucleotidyltransferase [Burkholderia pseudomallei... PNP_BURPS - Polyribonucleotide nucleotidyltransferase OS=Burkholderia pseudomallei (strain K96243) GN=pnp PE=3 S... PNP_BURP1 - Polyribonucleotide nucleotidyltransferase OS=Burkholderia pseudomallei (strain 1710b) GN=pnp PE=3 SV... gi\|167815032 - gi\|167815032\|ref\|ZP_02446712.1\| polynucleotide phosphorylase/polyadenylase [Burkholderia pseudomalle... gi\|100061234, gi... - gi\|67754596\|ref\|ZP_00493502.1\| COG1185: Polyribonucleotide nucleotidyltransferase (polynucleotide ph... gi\|167823448 - gi\|167823448\|ref\|ZP_02454919.1\| polynucleotide phosphorylase/polyadenylase [Burkholderia pseudomalle... gi\|167718839 - gi\|167718839\|ref\|ZP_02402075.1\| polynucleotide phosphorylase/polyadenylase [Burkholderia pseudomalle... gi\|167737848 - gi\|167737848\|ref\|ZP_02410622.1\| polynucleotide phosphorylase/polyadenylase [Burkholderia pseudomalle... gi\|167901988 - gi\|167901988\|ref\|ZP_02489193.1\| polynucleotide phosphorylase/polyadenylase [Burkholderia pseudomalle... gi\|167910223 - gi\|167910223\|ref\|ZP_02497314.1\| polynucleotide phosphorylase/polyadenylase [Burkholderia pseudomalle... gi\|167845000 - gi\|167845000\|ref\|ZP_02470508.1\| polynucleotide phosphorylase/polyadenylase [Burkholderia pseudomalle... gi\|134244712, gi... - gi\|134283923\|ref\|ZP_01770619.1\| polyribonucleotide nucleotidyltransferase [Burkholderia pseudomallei... gi\|167893541 - gi\|167893541\|ref\|ZP_02480943.1\| polynucleotide phosphorylase/polyadenylase [Burkholderia pseudomalle... PNP_BURP6 - Polyribonucleotide nucleotidyltransferase OS=Burkholderia pseudomallei (strain 668) GN=pnp PE=3 SV=1 PNP_BURP0 - Polyribonucleotide nucleotidyltransferase OS=Burkholderia pseudomallei (strain 1106a) GN=pnp PE=3 SV... gi\|254258157, gi... - gi\|67683891\|ref\|ZP_00477931.1\| COG1185: Polyribonucleotide nucleotidyltransferase (polynucleotide ph... gi\|226195372, gi... - gi\|226195372\|ref\|ZP_03790961.1\| polyribonucleotide nucleotidyltransferase [Burkholderia pseudomallei... gi\|242315054, gi... - gi\|82535997\|ref\|ZP_00895007.1\| hypothetical protein Bpse110_02002696 [Burkholderia pseudomallei 1106... PNP_BURPS - Polyribonucleotide nucleotidyltransferase OS=Burkholderia pseudomallei GN=pnp PE=3 SV=1 gi\|237503430, gi... - gi\|237811578\|ref\|YP_002896029.1\| polyribonucleotide nucleotidyltransferase [Burkholderia pseudomalle...	272.0	[0..3]	[238..315]
gi\|254181191, gi... - gi\|99909798\|ref\|ZP_01316909.1\| hypothetical protein Bpse1_03003728 [Burkholderia pseudomallei 1655],...	272.0	[0..3]	[238..315]
gi\|254202114, gi... - gi\|83620240\|ref\|ZP_00930662.1\| COG1185: Polyribonucleotide nucleotidyltransferase (polynucleotide ph... gi\|194316464, gi... - gi\|254175718\|ref\|ZP_04882378.1\| polyribonucleotide nucleotidyltransferase [Burkholderia mallei ATCC ... gi\|194527328, gi... - gi\|83623824\|ref\|ZP_00934085.1\| COG1185: Polyribonucleotide nucleotidyltransferase (polynucleotide ph... gi\|238523292, gi... - gi\|67642196\|ref\|ZP_00440956.1\| polyribonucleotide nucleotidyltransferase (Polynucleotidephosphorylas... PNP_BURM7 - Polyribonucleotide nucleotidyltransferase OS=Burkholderia mallei (strain NCTC 10247) GN=pnp PE=3 SV=... PNP_BURM9 - Polyribonucleotide nucleotidyltransferase OS=Burkholderia mallei (strain NCTC 10229) GN=pnp PE=3 SV=... gi\|167000372, gi... - gi\|243063706\|gb\|EES45892.1\| polyribonucleotide nucleotidyltransferase [Burkholderia mallei PRL-20], ... PNP_BURMA - Polyribonucleotide nucleotidyltransferase OS=Burkholderia mallei (strain ATCC 23344) GN=pnp PE=3 SV=... PNP_BURMS - Polyribonucleotide nucleotidyltransferase OS=Burkholderia mallei (strain SAVP1) GN=pnp PE=3 SV=1 gi\|85065184 - gi\|85065184\|ref\|ZP_01026037.1\| COG1185: Polyribonucleotide nucleotidyltransferase (polynucleotide ph... PNP_BURMA - Polyribonucleotide nucleotidyltransferase OS=Burkholderia mallei GN=pnp PE=3 SV=1 gi\|87314816, gi\|... - gi\|87314816\|ref\|ZP_01095854.1\| COG1185: Polyribonucleotide nucleotidyltransferase (polynucleotide ph...	272.0	[0..3]	[238..315]

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Predicted Domain #1

Region A:
Residues: [1-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIISEHGFR IDGRRPAQIR NINTRLGLNR NAEGSCYLEH GNTKVLCAVY GPYEGKSSKR  60
   61 IEDKCAIVCQ YSATKFSGLE RKNRTRGDRK STEISRLLEK AFESVILTEA FPRSQLDIFC 120
  121 EVIQGDGSNL AACVNATSLA LADAGIPMKG IASAATCGVV DGKPIVDLTS REETDLLPRV 180
  181 TLATICGRDE VILVELQNRL HIDHLSTVMD AAKATCADVY ECLAVVAQQH LKACAPILGN 240
  241

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.69897
Match:	2nn6B
Description:	No description for 2nn6B was found.

Predicted functions:

Term	Confidence	Notes
exoribonuclease activity	7.55877202113513	bayes_pls_golite062009
ribonuclease activity	7.54644729272203	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	7.5310318714913	bayes_pls_golite062009
3'-5'-exoribonuclease activity	6.46930372693262	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	5.06256868878098	bayes_pls_golite062009
exonuclease activity	4.6643790818023	bayes_pls_golite062009
3'-5' exonuclease activity	4.29895100594643	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.86434572018929	bayes_pls_golite062009
RNA binding	2.05527376734941	bayes_pls_golite062009
structural constituent of ribosome	1.90115575554186	bayes_pls_golite062009
structural molecule activity	1.69321127364043	bayes_pls_golite062009
hydrolase activity	1.55476709794855	bayes_pls_golite062009
binding	1.3018457178158	bayes_pls_golite062009
transcription regulator activity	1.20748032530392	bayes_pls_golite062009
mRNA binding	1.17402119891853	bayes_pls_golite062009
nucleic acid binding	1.05662964529454	bayes_pls_golite062009
catalytic activity	0.878454819018611	bayes_pls_golite062009
DNA binding	0.828609700556836	bayes_pls_golite062009
nuclease activity	0.69721312877891	bayes_pls_golite062009
carbohydrate kinase activity	0.51810239718467	bayes_pls_golite062009
tRNA-specific ribonuclease activity	0.383567539949931	bayes_pls_golite062009
deacetylase activity	0.2046781383773	bayes_pls_golite062009
ATP-dependent peptidase activity	0.1173709890655	bayes_pls_golite062009
protein binding	0.0913090112555771	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.0287026367466632	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: