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View Structure Prediction Details

Protein: egl-4
Organism: Caenorhabditis elegans
Length: 737 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for egl-4.

Description E-value Query
Range
Subject
Range
egl-4 - cyclic-GMP-dependent protein kinase status:Confirmed UniProt:O76360 protein_id:AAD36954.1
583.0 [0..4] [737..47]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQQPPRIYV QVGTRTFEAH ELQKLIPQLE EAISRKDAQL RQQQTIVEGH IKRISELEGE  60
   61 VTTLQRECDK LRSVLEQKAQ SAASPGGQPP SPSPRTDQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.221849
Match: 2ezwA
Description: Solution structure of the docking and dimerization domain of the type I alpha regulatory subunit of protein kinase A (RIalpha D/D)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [99-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGNDLQQKAV LPADGVQRAK KIAVSAEPTN FENKPATLQH YNKTVGAKQM IRDAVQKNDF  60
   61 LKQLAKEQII ELVNCMYEMR ARAGQWVIQE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.69897
Match: 1rgsA
Description: REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [189-673]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEPGDRLFVV AEGELQVSRE GALLGKMRAG TVMGELAILY NCTRTASVQA LTDVQLWVLD  60
   61 RSVFQMITQR LGMERHSQLM NFLTKVSIFQ NLSEDRISKM ADVMDQDYYD GGHYIIRQGE 120
  121 KGDAFFVINS GQVKVTQQIE GETEPREIRV LNQGDFFGER ALLGEEVRTA NIIAQAPGVE 180
  181 VLTLDRESFG KLIGDLESLK KDYGDKERLA QVVREPPSPV KIVDDFREEF AQVTLKNVKR 240
  241 LATLGVGGFG RVELVCVNGD KAKTFALKAL KKKHIVDTRQ QEHIFAERNI MMETSTDWIV 300
  301 KLYKTFRDQK FVYMLLEVCL GGELWTTLRD RGHFDDYTAR FYVACVLEGL EYLHRKNIVY 360
  361 RDLKPENCLL ANTGYLKLVD FGFAKKLASG RKTWTFCGTP EYVSPEIILN KGHDQAADYW 420
  421 ALGIYICELM LGRPPFQASD PMKTYTLILK GVDALEIPNR RIGKTATALV KKLCRDNPGE 480
  481 RLGSG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.30103
Match: 2ozoA
Description: No description for 2ozoA was found.

Predicted Domain #4
Region A:
Residues: [674-737]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGGVNDIRKH RWFMGFDWEG LRSRTLKPPI LPKVSNPADV TNFDNYPPDN DVPPDEFSGW  60
   61 DEGF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.69897
Match: 2gnfA
Description: No description for 2gnfA was found.

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