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View Structure Prediction Details

Protein: ast-1
Organism: Caenorhabditis elegans
Length: 377 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ast-1.

Description E-value Query
Range
Subject
Range
gi|114684166 - gi|114684166|ref|XP_531459.2| PREDICTED: v-ets erythroblastosis virus E26 oncogene homolog 2 isoform...
232.0 [0..25] [327..254]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVVSSATLP PTVASADLAI VGGRSSDEDV IKYSAIQTIK QEQQQQQQQQ SNTALPSYNF  60
   61 PFFNGMQNDF PPNRMLYNDN TMQKSENDHF TGMNLSTSAS SSGNSTSSKD QSRRQFYTES 120
  121 SNSSGNGAAA TSGSNGSSSS TESKSDVFNI SMNAFAATPG SKSEDHNIPS FNMLSSYYTG 180
  181 ALK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [184-377]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSNSTSFANP DPYQILGPTS KNLAHSGSGQ TQLWQFLLEL LSDKRYSEVI TWEGTQGEFK  60
   61 LVDPDEVARK WGERKSKPNM NYDKMSRALR YYYDKNIMAK VHGKRYAYKF DFQGIAQALQ 120
  121 PPTASHPQDY FNSHAMGRIA PDFSSWTSAN YRSLNIAGFN NGSTIFNPSV NYSAFGATGT 180
  181 SNNLSAARAF PLYR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.221849
Match: 1fliA
Description: Fli-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.75235002882976 bayes_pls_golite062009
transcription regulator activity 1.40837731591833 bayes_pls_golite062009
DNA binding 1.24351754120608 bayes_pls_golite062009
nucleic acid binding 1.06033428483031 bayes_pls_golite062009
transcription factor activity 0.76402352618699 bayes_pls_golite062009
protein binding 0.058151715836892 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle