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View Structure Prediction Details

Protein: acdh-9
Organism: Caenorhabditis elegans
Length: 409 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acdh-9.

Description E-value Query
Range
Subject
Range
gi|77996195, gi|... - gi|78044080|ref|YP_360183.1| butyryl-CoA dehydrogenase [Carboxydothermus hydrogenoformans Z-2901], g...
472.0 [0..23] [403..1]

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Predicted Domain #1
Region A:
Residues: [1-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLRNVLSKG LRLRNSSSYC LRPGVGLERD VEDVLEAAHQ FAKKEMYPKM ADWDKQGELP  60
   61 MDVLRKAGEM GFGAIYCSGD HGGSGLSRLH ASVIFEQLSM GCVSTAAYIS IHNMCAWMLD 120
  121 TYGPEKLKED LLPDMAVFKK LGSYCLTEPD AGSDAASIRT TATKKGDYYV VNGSKAFISG 180
  181 AGTSNNYFVM MRQDGAAPGA KGIFCLMIED GTEGFSYGKK EDKLGWNSQP TRILTFEDCK 240
  241 VPITNQIGKD GFGFNIAMAG LNGGRINIAS CSLGAAQRSM DLAIEHLKYR KQFGKSLADF 300
  301 QYNQFKLAEL ATKLYTSRLI VRNAAEQLDN DDPEKVALCA MAKLHATDNC FDVVNGALQM 360
  361 FGGYGFLKDY PVQQYLRDIR VHQILEGTNE MMRLLISRDL LTKDVFWSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.0
Match: 1rx0A
Description: Crystal structure of isobutyryl-CoA dehydrogenase complexed with substrate/ligand.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
acyl-CoA oxidase activity 7.85164875699474 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 7.69964776555327 bayes_pls_golite062009
acyl-CoA dehydrogenase activity 6.0252876667118 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 5.78129971677842 bayes_pls_golite062009
isovaleryl-CoA dehydrogenase activity 4.66102768687662 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 4.57415724042946 bayes_pls_golite062009
oxidoreductase activity 3.99827953439804 bayes_pls_golite062009
RNA polymerase II transcription mediator activity 3.58504058273727 bayes_pls_golite062009
catalytic activity 2.41506805547596 bayes_pls_golite062009
transcription regulator activity 2.31681514717218 bayes_pls_golite062009
pristanoyl-CoA oxidase activity 2.26651221125135 bayes_pls_golite062009
binding 1.84962038137824 bayes_pls_golite062009
palmitoyl-CoA oxidase activity 1.72613267428428 bayes_pls_golite062009
long-chain-acyl-CoA dehydrogenase activity 1.53039234278399 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.634990683062526 bayes_pls_golite062009
butyryl-CoA dehydrogenase activity 0.400090490265931 bayes_pls_golite062009
protein binding 0.0853302624128481 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle