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View Structure Prediction Details

Protein: tpi-1
Organism: Caenorhabditis elegans
Length: 247 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tpi-1.

Description E-value Query
Range
Subject
Range
gi|109505678 - gi|109505678|ref|XP_001064421.1| PREDICTED: similar to triosephosphate isomerase [Rattus norvegicus]
374.0 [0..2] [246..4]
TPI1 - triosephosphate isomerase 1
TPIS_PANTR - Triosephosphate isomerase OS=Pan troglodytes GN=TPI1 PE=2 SV=2
gi|123993147, gi... - gi|124000137|gb|ABM87577.1| triosephosphate isomerase 1 [synthetic construct], gi|123993147|gb|ABM84...
373.0 [0..2] [246..4]
gi|223374 - gi|223374|prf||0801190A isomerase,triosephosphate
TPIS_RABIT - Triosephosphate isomerase OS=Oryctolagus cuniculus GN=TPI1 PE=1 SV=1
373.0 [0..2] [246..3]
gi|55730014 - gi|55730014|emb|CAH91732.1| hypothetical protein [Pongo abelii]
TPIS_PONAB - Triosephosphate isomerase OS=Pongo abelii GN=TPI1 PE=2 SV=1
373.0 [0..2] [246..4]

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Predicted Domain #1
Region A:
Residues: [1-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRKFFVGGN WKMNGDYASV DGIVTFLNAS ADNSSVDVVV APPAPYLAYA KSKLKAGVLV  60
   61 AAQNCYKVPK GAFTGEISPA MIKDLGLEWV ILGHSERRHV FGESDALIAE KTVHALEAGI 120
  121 KVVFCIGEKL EEREAGHTKD VNFRQLQAIV DKGVSWENIV IAYEPVWAIG TGKTASGEQA 180
  181 QEVHEWIRAF LKEKVSPAVA DATRIIYGGS VTADNAAELG KKPDIDGFLV GGASLKPDFV 240
  241 KIINARS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.0
Match: 1mo0A
Description: Triosephosphate isomerase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
triose-phosphate isomerase activity 5.94525596131351 bayes_pls_golite062009
intramolecular oxidoreductase activity 4.11751506069887 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses 3.62219160185043 bayes_pls_golite062009
isomerase activity 2.06271139232842 bayes_pls_golite062009
binding 1.80264931081179 bayes_pls_golite062009
catalytic activity 1.7524198174984 bayes_pls_golite062009
protein binding 0.33788557654084 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle