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View Structure Prediction Details

Protein: atg-7
Organism: Caenorhabditis elegans
Length: 647 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for atg-7.

Description E-value Query
Range
Subject
Range
gi|73984600 - gi|73984600|ref|XP_849849.1| PREDICTED: similar to APG7 autophagy 7-like isoform 3 [Canis familiaris...
556.0 [0..4] [645..15]

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Predicted Domain #1
Region A:
Residues: [1-143]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATFVPFVTC LDTGFWNEVN KKKLNDWKLD ETPKCISSQL SLHQTEGFKC HLSLSYDSLS  60
   61 SLESTTGLSM SGTLLLYNTI ESFKMVDKSD LIRSEAEKIW ESITTRKWLQ NPRLLSQFFI 120
  121 IAFADLKKFK YYYWTCVPAL VYP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [144-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEIKQEITPL SSLGADHKIL FDFYRKNNFP IFLYSKQSSK MLELSELENN TNPDEICVVV  60
   61 ADPSPVAYSA GWMVRNVLAA VAHLHPTWKH CHIISLRSAD SIGIKYTWTL PSAECSADGA 120
  121 QNAVPKAVGW ERNANDKLQP ISVDLSK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [291-647]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFDPKILMER SVDLNLSLIK WRLHPDIQLE RYSQLKVLIL GAGTLGCNIA RCLIGWGVRH  60
   61 ISFLDNSTVS YNNPVRQSLS EFEDARLGRG KAETAQAAIQ RIFPSIQATA HRLTVPMPGH 120
  121 SIDEKDVPEL EKDIAKLEQL VKDHDVVFLA LDSREARWLP TVLASRHKKI AISVAIGFDT 180
  181 YVIIRHGIGS RSESVSDVSS SDSVPYSQLS CYFCSDVTAP GNSTFDRTLD QQCTVARPGT 240
  241 SMIASGIAVE LLSSVLQYPD PLKTPASHDD NTTVLGAAPH QIRGFLGRFQ QILPSVKRFD 300
  301 QCVACGDAIA AQFQQNGWKF VRDVMNSPGR LEEVTGLDEL QNSVNAIDID FEDDEDF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.30103
Match: 1jw9B
Description: Molybdenum cofactor biosynthesis protein MoeB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small protein activating enzyme activity 3.58068602287881 bayes_pls_golite062009
NEDD8 activating enzyme activity 2.11391077579348 bayes_pls_golite062009
small conjugating protein ligase activity 1.84216910649062 bayes_pls_golite062009
binding 1.66028321721112 bayes_pls_golite062009
transcription regulator activity 1.54883560427918 bayes_pls_golite062009
protein binding 1.40907622346701 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.31244773198273 bayes_pls_golite062009
acid-amino acid ligase activity 1.27535252106053 bayes_pls_golite062009
catalytic activity 1.22201444897049 bayes_pls_golite062009
transferase activity 0.680338489823338 bayes_pls_golite062009
URM1 activating enzyme activity 0.207228630005671 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle