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View Structure Prediction Details

Protein: gst-25
Organism: Caenorhabditis elegans
Length: 208 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gst-25.

Description E-value Query
Range
Subject
Range
gi|28630830 - gi|28630830|gb|AAO45827.1| glutathione S-transferase [Wuchereria bancrofti]
183.0 [0..1] [208..1]
gi|2058287 - gi|2058287|emb|CAA73325.1| glutathione transferase [Brugia malayi]
182.0 [0..1] [208..1]
gi|1943418, gi|1... - gi|1943419|pdb|2GSR|B Chain B, Structure Of Porcine Class Pi Glutathione S-Transferase, gi|1943418|p...
179.0 [0..2] [208..2]
GSTP_DIRIM - Glutathione S-transferase OS=Dirofilaria immitis PE=2 SV=1
175.0 [0..1] [208..1]
gi|157775897 - gi|157775897|ref|XP_001666014.1| hypothetical protein CBG06825 [Caenorhabditis briggsae AF16]
gi|39585029, gi|... - gi|39585029|emb|CAE62680.1| Hypothetical protein CBG06825 [Caenorhabditis briggsae], gi|187033779|em...
175.0 [0..1] [208..1]
GSTP1_CRILO - Glutathione S-transferase P OS=Cricetulus longicaudatus GN=GSTP1 PE=2 SV=2
gi|7434045, gi|6... - gi|7434045|pir||S71959 glutathione transferase (EC 2.5.1.18) class pi - Chinese hamster, gi|695303|g...
174.0 [0..2] [208..3]
gi|2624495, gi|2... - gi|2624496|pdb|1BAY|B Chain B, Glutathione S-Transferase Yfyf Cys 47-Carboxymethylated Class Pi, Fre...
174.0 [0..2] [208..2]
GSTP1_CRIMI - Glutathione S-transferase P OS=Cricetulus migratorius GN=GSTP1 PE=2 SV=2
173.0 [0..2] [208..3]

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Predicted Domain #1
Region A:
Residues: [1-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLKFSYFGT RGIGEPIRML LTDQEVAFID HRFSWEQWAD IKPTMIFGSC PCLTMGDKEI  60
   61 VQSGTIIRHL ARIHGLNGTN EEETIFIDMF YEGVRDLHAT YATMIYQNYE NGRQPFIQDV 120
  121 LPEHLARLEK LFRTYENGEN FVAGANISYV DYVLFEELDI QKILSPTALD RTPQLKKFHE 180
  181 QFGERKNLTE YLKKRAIMKT PVNGNGKQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.69897
Match: 1tu7A
Description: Structure of Onchocerca Volvulus Pi-class Glutathione S-transferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glutathione transferase activity 4.50796867464992 bayes_pls_golite062009
prostaglandin-D synthase activity 3.77818075962089 bayes_pls_golite062009
glutathione binding 3.70571520983029 bayes_pls_golite062009
antioxidant activity 3.66884588063322 bayes_pls_golite062009
peroxidase activity 3.43831566988273 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.43831566988273 bayes_pls_golite062009
glutathione peroxidase activity 2.56524997297011 bayes_pls_golite062009
selenium binding 2.55069860113032 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.8187537496904 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
molecular transducer activity 1.03696928411308 bayes_pls_golite062009
signal transducer activity 1.03696928411308 bayes_pls_golite062009
phospholipid-hydroperoxide glutathione peroxidase activity 0.874146425427531 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
transcription regulator activity 0.52671047749426 bayes_pls_golite062009
receptor binding 0.430107649265259 bayes_pls_golite062009
maleylacetoacetate isomerase activity 0.426921894831614 bayes_pls_golite062009
DNA binding 0.278017923256183 bayes_pls_golite062009
nucleic acid binding 0.27489371858599 bayes_pls_golite062009
protein binding 0.134341907247724 bayes_pls_golite062009
protein disulfide oxidoreductase activity 0.0719543694089202 bayes_pls_golite062009
transcription repressor activity 0.00678211696545472 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle