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View Structure Prediction Details

Protein: ife-3
Organism: Caenorhabditis elegans
Length: 248 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ife-3.

Description E-value Query
Range		 Subject
Range
ife-3 - status:Partially_confirmed UniProt:O61955 protein_id:AAM22022.1
 363.0 [0..1] [248..1]
gi|39592694, gi|... - gi|39592694|emb|CAE62308.1| Hypothetical protein CBG06370 [Caenorhabditis briggsae], gi|187033964|em...
 310.0 [0..1] [233..1]
gi|67969074 - gi|67969074|dbj|BAE00892.1| unnamed protein product [Macaca fascicularis]
 305.0 [0..14] [212..44]
gi|94370433 - gi|94370433|ref|XP_930840.2| PREDICTED: similar to eIF-4E [Mus musculus]
 303.0 [0..12] [212..17]
IF4E_XENLA - Eukaryotic translation initiation factor 4E OS=Xenopus laevis GN=eif4e PE=1 SV=1
 303.0 [0..3] [212..4]
IF4E_MOUSE - Eukaryotic translation initiation factor 4E OS=Mus musculus GN=Eif4e PE=1 SV=1
IF4E_RAT - Eukaryotic translation initiation factor 4E OS=Rattus norvegicus GN=Eif4e PE=1 SV=1
 302.0 [0..12] [212..17]
IF4E_RABIT - Eukaryotic translation initiation factor 4E OS=Oryctolagus cuniculus GN=EIF4E PE=1 SV=1
 301.0 [0..14] [212..21]
gi|60830630 - gi|60830630|gb|AAX36938.1| eukaryotic translation initiation factor 4E [synthetic construct]
 301.0 [0..14] [212..21]
gi|56090190, gi|... - gi|56090190|ref|NP_001007778.1| eukaryotic translation initiation factor 4E [Danio rerio], gi|557160...
 301.0 [0..1] [212..1]

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Predicted Domain #1
Region A:
Residues: [1-248] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTSVAENKA LSASGDVNAS DASVPPELLT RHPLQNRWAL WYLKADRNKE WEDCLKMVSL  60
   61 FDTVEDFWSL YNHIQSAGGL NWGSDYYLFK EGIKPMWEDV NNVQGGRWLV VVDKQRRTQL 120
  121 LDHYWLELLM AIVGEQFDEY GDYICGAVVN VRQKGDKVSL WTRDATRDDV NLRIGQVLKQ 180
  181 KLSIPDTEIL RYEVHKDSSA RTSSTVKPRI CLPAKDPAPV KEKGPAATTS PSNPGTEATG 240
  241 TSPATPTP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 82.0
Match: 1ipbA
Description: Translation initiation factor eIF4e
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation initiation factor activity 12.6022960879923 bayes_pls_golite062009
RNA cap binding 8.70938037002519 bayes_pls_golite062009
translation factor activity, nucleic acid binding 7.91586572659635 bayes_pls_golite062009
translation regulator activity 7.87578736455963 bayes_pls_golite062009
RNA binding 6.31187636707846 bayes_pls_golite062009
binding 3.48071223822752 bayes_pls_golite062009
nucleic acid binding 3.46353214508261 bayes_pls_golite062009
protein binding 0.850113401405075 bayes_pls_golite062009
RNA 7-methylguanosine cap binding 0.544036568660606 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle