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View Structure Prediction Details

Protein: CE16843
Organism: Caenorhabditis elegans
Length: 394 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE16843.

Description E-value Query
Range
Subject
Range
gi|118344558, gi... - gi|55771082|dbj|BAD69801.1| cathepsin D1 [Takifugu rubripes], gi|118344558|ref|NP_001072052.1| cathe...
340.0 [0..1] [392..1]

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Predicted Domain #1
Region A:
Residues: [1-394]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALPFFLLLP NAHFSSFCMH LVRKEHSTCL MGPVVSNRLH SSSFKSKHTI HKGQHQHVAD  60
   61 FRDFAYFGNI TLGTPIESTA EQTFLVVLDT GSSNVWVPDN SCGIDDKKSA CTYKKKYFGT 120
  121 DSSSYEKDGT PFSISYGTGS ASGYFGKDTL CFSDTTLCIK SQIFGQANNI APFFANQEID 180
  181 GILGLGFTDL AVHSVPPPFV NAVEQGLVDE PIFTVYLEHH GIKKEASGGY FTYGGEDPDH 240
  241 CGEIITWIPL TKAAYWQFRM QGIGIDNVNE HKNGWEVISD TGTSFIGGPG KVIQDIANKY 300
  301 GATYDEYSDS YVIPCSEIKN LRSLKMKIND LTFEIDPINL VAHPDSSECD LTLFDMYGGG 360
  361 FGPSWILGDP FIRQFCNIHD IKNKRIGLAH SKQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 82.0
Match: 2psgA
Description: REFINED STRUCTURE OF PORCINE PEPSINOGEN AT 1.8 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aspartic-type endopeptidase activity 7.9145950161796 bayes_pls_golite062009
aspartic-type peptidase activity 7.9145950161796 bayes_pls_golite062009
peptidase activity 5.78181196721293 bayes_pls_golite062009
endopeptidase activity 5.4888481808613 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 5.39972232367526 bayes_pls_golite062009
hydrolase activity 4.34796304893506 bayes_pls_golite062009
catalytic activity 1.54514410489082 bayes_pls_golite062009
binding 0.902062095182608 bayes_pls_golite062009
receptor binding 0.561225023505917 bayes_pls_golite062009
protein binding 0.094081389440774 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle