YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: nhr-112
Organism: Caenorhabditis elegans
Length: 342 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-112.

Description E-value Query
Range
Subject
Range
gi|68396885 - gi|68396885|ref|XP_683221.1| PREDICTED: similar to retinoid X receptor-alpha [Danio rerio]
252.0 [0..1] [341..207]

Back

Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCKICGSSES EPHFGGTSCR ACAAFFRRFY HSKKLGLKCT CKTRQSNAHP CRSCRIRKCY  60
   61 EAGMTPEKIQ LTRDKHLNRT 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.0
Match: 2hanB
Description: No description for 2hanB was found.

Predicted functions:

Term Confidence Notes
binding 1.18770607371139 bayes_pls_golite062009
protein binding 0.699012253331291 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [81-342]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKLEGPCSSL DTPITSRQTP NLYCVLSNWH ELKMTREEMN SGSLNNCNIF ELTSFVLRDL  60
   61 ELTWRMVSKA FPTVEVLEDR DRQALLRNFV PKLWQIEPIL EYRECAEKFD NLEEEDYENL 120
  121 LVGFYGGTFP EGKEMSKSEI VSNFRPYWDY YYTKMILPIS SMGLEELEYM AIVWLAFFDN 180
  181 GYSNISDNCL EMCRDIQKVI LKELRNYQID RNFHENRFFV ALEALQIIER GEKKFMEEML 240
  241 VCEMNHIRIH DDFRKIIREP KL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.30103
Match: 1lbdA
Description: LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.07679393058916 bayes_pls_golite062009
protein binding 1.4692467191721 bayes_pls_golite062009
transcription regulator activity 1.38569381220638 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.33970394025402 bayes_pls_golite062009
receptor activity 1.27827487658808 bayes_pls_golite062009
DNA binding 1.07558579137079 bayes_pls_golite062009
signal transducer activity 0.875578759851886 bayes_pls_golite062009
molecular transducer activity 0.875578759851886 bayes_pls_golite062009
nucleic acid binding 0.843756208408716 bayes_pls_golite062009
transcription factor activity 0.523911554416 bayes_pls_golite062009
sequence-specific DNA binding 0.14253203697325 bayes_pls_golite062009
transcription activator activity 0.0654022419611198 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle