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View Structure Prediction Details

Protein: CE16009
Organism: Caenorhabditis elegans
Length: 328 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE16009.

Description E-value Query
Range
Subject
Range
gi|86134306, gi|... - gi|86134306|ref|ZP_01052888.1| zinc-binding dehydrogenase [Polaribacter sp. MED152], gi|85821169|gb|...
316.0 [0..8] [326..10]

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Predicted Domain #1
Region A:
Residues: [1-328]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSICKSSM RAAVVRRFGA PDVIEAVESD MPRLEKNQVL VRNYAAGVNP VDTYIRAGQY  60
   61 GKLPNLPYVP GKDGAGFVEL VGESVKNVKV GDRVWYGSEA DSTAEYVAVN RPFELPEGVS 120
  121 FEEGASLGVP YLTAYRALFH LAGAKTGDVI LVHGASGGVG SALMQLAAWR NIEAVGTAGS 180
  181 ADGIRFVKSL GARNVYNHSD KQYVSKMKND YPGGFNHIFE MAAHTNLNTD LGLLAPRGRV 240
  241 AVIGNRAETT INARQLMVTE GAVYGVALGM SSEAELLDFG INIVSFLKET EFRPLINKLY 300
  301 RLEQLGLAHE EIMNNKGAKG NLVVQIEH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.522879
Match: 1yb5A
Description: Crystal structure of human Zeta-Crystallin with bound NADP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 3.09625241707629 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 2.94416173750168 bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent 2.26153457113968 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.65338499044318 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.47309297191111 bayes_pls_golite062009
fatty acid synthase activity 1.23679054027553 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 1.22416351603098 bayes_pls_golite062009
chaperone binding 1.04678886151518 bayes_pls_golite062009
binding 0.982999356179965 bayes_pls_golite062009
DNA binding 0.940078857029005 bayes_pls_golite062009
transcription regulator activity 0.854100257756792 bayes_pls_golite062009
RNA binding 0.843556706364142 bayes_pls_golite062009
transporter activity 0.793769336118517 bayes_pls_golite062009
nucleic acid binding 0.787328837435283 bayes_pls_golite062009
transmembrane transporter activity 0.635891484075352 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 0.62461633437589 bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity 0.604742541607263 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.576163737662951 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.51503848775098 bayes_pls_golite062009
protein binding 0.507836099271263 bayes_pls_golite062009
retinol dehydrogenase activity 0.48941662111046 bayes_pls_golite062009
NAD or NADH binding 0.44922383360529 bayes_pls_golite062009
transcription factor activity 0.35056694435192 bayes_pls_golite062009
substrate-specific transporter activity 0.300373102236296 bayes_pls_golite062009
active transmembrane transporter activity 0.239024094835991 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 0.233238483713519 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.165260811069909 bayes_pls_golite062009
ion transmembrane transporter activity 0.0257250793986203 bayes_pls_golite062009

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