YRC Public Data Repository - Protein Structure Prediction

Protein:	lbp-6
Organism:	Caenorhabditis elegans
Length:	135 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lbp-6.

Description	E-value	Query Range	Subject Range
gi\|114658435 - gi\|114658435\|ref\|XP_001142851.1\| PREDICTED: similar to cellular retinoic acid-binding protein; CRABP...	187.0	[0..1]	[135..245]
gi\|182891550, gi... - gi\|60552807\|gb\|AAH91464.1\| Crabp1a protein [Danio rerio], gi\|33504499\|ref\|NP_878278.1\| cellular reti...	176.0	[0..1]	[135..1]
IPI:IPI00190799.... - Ensembl_locations(Chr-bp):None Retinoic acid-binding protein I, cellular RET3_BOVIN, RABP... - (P62964) Retinoic acid-binding protein I, cellular (CRABP-I), (P62964) Cellular retinoic acid-bindin... RABP1_MOUSE, RET... - (P62965) Retinoic acid-binding protein I, cellular (CRABP-I), (P62965) Cellular retinoic acid-bindin...	171.0	[0..3]	[135..1]
RABP1_CHICK - Cellular retinoic acid-binding protein 1 OS=Gallus gallus GN=CRABP1 PE=2 SV=4	171.0	[0..3]	[135..2]
FABPH_PIG - Fatty acid-binding protein, heart OS=Sus scrofa GN=FABP3 PE=2 SV=3	171.0	[0..1]	[135..1]
CRABP1 - cellular retinoic acid binding protein 1 ENSPTRT00000013536 - null gi\|149691749 - gi\|149691749\|ref\|XP_001488972.1\| PREDICTED: similar to Cellular retinoic acid-binding protein 1 (Cel... ENSCJAT00000019948 - null gi\|148470135, gi... - gi\|190360581\|ref\|NP_001121964.1\| cellular retinoic acid binding protein 1 [Sus scrofa], gi\|148470135... gi\|109082058 - gi\|109082058\|ref\|XP_001107715.1\| PREDICTED: cellular retinoic acid binding protein 1 [Macaca mulatta...	170.0	[0..3]	[135..2]
FABP7_BOVIN - Fatty acid-binding protein, brain OS=Bos taurus GN=FABP7 PE=1 SV=2	169.0	[0..1]	[134..1]

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Predicted Domain #1

Region A:
Residues: [1-135]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQEFVGRWK LIHSENFEEY MKEVGVGLIT RKAAANLKPT LEIKVEGDLW YSNQYSTFKN  60
   61 TTLSFKLGQE FDETTPDGRT VKSVVNFENG KFIHIQKKIK DSDKESIITR WLEGDKLITT 120
  121 LESGSVVSRR EYVRE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.39794
Match:	1cbiA
Description:	Cellular retinoic-acid-binding protein (CRABP)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
long-chain fatty acid transporter activity	4.03130183716737	bayes_pls_golite062009
retinoid binding	3.86745158299736	bayes_pls_golite062009
isoprenoid binding	3.80802424204178	bayes_pls_golite062009
fatty acid transporter activity	3.78208104687342	bayes_pls_golite062009
retinol binding	3.41359399354212	bayes_pls_golite062009
binding	2.93830472620404	bayes_pls_golite062009
transcription regulator activity	2.27413749831465	bayes_pls_golite062009
lipid transporter activity	1.7304520084656	bayes_pls_golite062009
transcription repressor activity	1.45696778890481	bayes_pls_golite062009
protein binding	1.23450129884619	bayes_pls_golite062009
prostaglandin-D synthase activity	1.18764036773412	bayes_pls_golite062009
lipid binding	1.0002255159651	bayes_pls_golite062009
retinol transporter activity	0.811095267558536	bayes_pls_golite062009
fatty acid binding	0.761923641769607	bayes_pls_golite062009
retinoic acid binding	0.539496110498594	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: