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View Structure Prediction Details

Protein: asd-2
Organism: Caenorhabditis elegans
Length: 403 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for asd-2.

Description E-value Query
Range
Subject
Range
asd-2 - status:Confirmed UniProt:Q65CM6 protein_id:AAU20839.1
294.0 [0..6] [403..48]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTHASTDLLT PNGSANGVST SQQQQYSAEY LSQLLKDKKQ LAAFPNVFHH LERLADEEIN  60
   61 KVRVVLFQCE FSKESAPLPD A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [82-246]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGDSTVHTEK VFVPAKEHPD YNFVGRILGP RGMTAKQLEQ ETGCKIMVRG RGSMRDKKKE  60
   61 ELNRGKPNWE HLSEELHVLI QCEDTENRAK VKLMRAVEEV RKLLVPAPEG EDDLKRKQLM 120
  121 ELAIINGTYR SGTDQSALAA AQLAAVKHQQ QPFAAALQAA ALQRG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.0
Match: 2bl5A
Description: Solution structure of the KH-QUA2 region of the Xenopus STAR-GSG Quaking protein.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 3.79066340213332 bayes_pls_golite062009
nucleic acid binding 3.1702329067388 bayes_pls_golite062009
mRNA binding 2.45375256113953 bayes_pls_golite062009
binding 2.12000404411947 bayes_pls_golite062009
transcription regulator activity 0.720255318931267 bayes_pls_golite062009
catalytic activity 0.483552478758071 bayes_pls_golite062009
protein binding 0.446932489882167 bayes_pls_golite062009
DNA binding 0.369815489813612 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [247-403]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLPMMANGLS RSPTMAVCGA PIVMSPSGRA SSAGATATSQ AALIMQQQSQ LHAANAGNAA  60
   61 LQQQAALLQQ QQAAEYQQLL LSQAGLYDFS AMQQQYAAVG QNAAVAAAQA QAQAQYGALA 120
  121 AAAAANSAGN QQYADYAGVD LTSQQSAHGG YYVRRWA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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