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View Structure Prediction Details

Protein: CE10464
Organism: Caenorhabditis elegans
Length: 543 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE10464.

Description E-value Query
Range
Subject
Range
gi|47228655 - gi|47228655|emb|CAG07387.1| unnamed protein product [Tetraodon nigroviridis]
164.0 [0..2] [434..26]

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Predicted Domain #1
Region A:
Residues: [1-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRRVTRSMG GSIASATIDT STPTTRLTTR KRTAQQQTPV DSSSSSSDAS DESFVACPVE  60
   61 AKRRKKKLTN SRKSTSELPE KKKTDKVNLQ RPDIKKALFE HFEKNPKPES ESLQKISAQL 120
  121 GLTQQQVTGW FNRRNGTYLI SGPHNSVSKA DRKLSHMTKK LGERIMEKFE SDDLPSVELK 180
  181 EQWAQELRTT VQKVHVLLYK TRAEVMKSYL NG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.221849
Match: 1gt0C
Description: Oct-1 POU Homeodomain; Oct-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.971797124886045 bayes_pls_golite062009
nucleic acid binding 0.74904610690468 bayes_pls_golite062009
DNA binding 0.73457854282882 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [213-439]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERADLPRKMK AILEAEYDKS DGVDDVHIRE CKDQCELSYS LIEEYFQMRR KAEQKAQENS  60
   61 VAQEVAHREV AQQEVVQQDQ DGPGSHQEVA QDQEIAEQSA VVAKTSIVVQ EVAEQGSEQE 120
  121 LDHPLLVENL ETICHRDNIR LFTDFHQKRK HPSHADFQNL SRQTGRSVEL IRHWFSLKNE 180
  181 SQEPEKTTSV SRISPIPVED AKQQVMELLK TDSNPSVYLK RQWAEQF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [440-543]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NISMCMISNW KAELENPAIA RVMAERKRTS NLDYASRILE QKFANRANLL PSDLVDLEKT  60
   61 IGWTLDEISE WFETREKLQE RRESSEAGRD FSSRSIKQEI ITIE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 2cueA
Description: Solution structure of the homeobox domain of the human paired box protein Pax-6
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.334577365229545 bayes_pls_golite062009
transcription regulator activity 0.0696342306231097 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle