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View Structure Prediction Details

Protein: CE09597
Organism: Caenorhabditis elegans
Length: 507 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE09597.

Description E-value Query
Range
Subject
Range
gi|187035401, gi... - gi|39589899|emb|CAE60897.1| Hypothetical protein CBG04612 [Caenorhabditis briggsae], gi|187035401|em...
gi|157765132 - gi|157765132|ref|XP_001674909.1| Hypothetical protein CBG04612 [Caenorhabditis briggsae AF16]
442.0 [0..1] [507..1]

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Predicted Domain #1
Region A:
Residues: [1-269]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKFPVPLRT IGGLRPSTTA AISAANIGFT QSSRALSTGA AAKSSGLVGQ VARQYPNAAA  60
   61 FSIKQVRLYS SGNLPKHNRV ALPALSPTME LGTVVSWQKK EGDQLSEGDL LCEIETDKAT 120
  121 MGFETPEEGY LAKILIQEGS KDVPIGKLLC IIVDNEADVA AFKDFKDDGA SSGGSAPAAE 180
  181 KAPEPAKPAA SSQPSPPAQM YQAPSVPKSA PIPHSSSGRV SASPFAKKLA AENGLDLSGV 240
  241 SGSGPGGRIL ASDLSQAPAK GATSTTTQA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.221849
Match: 1zy8K
Description: The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [270-507]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSGQDYTDIP LSNMRKTIAK RLTESKSTIP HYYLTSEIQL DTLLQVREKL NGLLAKGTSG  60
   61 QATKISINDF IIKASALACQ RVPEANSYWM DSFIRENHHV DVSVAVSTPA GLITPIIFNA 120
  121 HAKGLATIAS EIVELAQRAR EGKLQPHEFQ GGTFTVSNLG MFGSVSDFTA IINPPQSCIL 180
  181 AIGGASDKLV PDEAEGYKKI KTMKVTLSCD HRTVDGAVGA VWLRHFKEFL EKPHTMLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.39794
Match: 1c4tA
Description: Dihydrolipoamide succinyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
dihydrolipoyllysine-residue acetyltransferase activity 9.65061123545754 bayes_pls_golite062009
dihydrolipoamide S-acyltransferase activity 9.64995677986911 bayes_pls_golite062009
S-acetyltransferase activity 9.49696044977584 bayes_pls_golite062009
S-acyltransferase activity 8.45313874919036 bayes_pls_golite062009
pyruvate dehydrogenase activity 8.17557182322815 bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity 6.40483178382327 bayes_pls_golite062009
acetyltransferase activity 6.08159176722072 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 5.93985773477717 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 5.74314131636952 bayes_pls_golite062009
acyltransferase activity 5.72047003788767 bayes_pls_golite062009
transferase activity, transferring acyl groups 4.60481199262496 bayes_pls_golite062009
S-succinyltransferase activity 4.47883105509359 bayes_pls_golite062009
dihydrolipoyllysine-residue succinyltransferase activity 4.47883105509359 bayes_pls_golite062009
alpha-ketoacid dehydrogenase activity 4.42757758312016 bayes_pls_golite062009
carnitine O-acyltransferase activity 2.87366177129153 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 2.54513901872655 bayes_pls_golite062009
succinyltransferase activity 2.08404693277798 bayes_pls_golite062009
catalytic activity 1.51562638409295 bayes_pls_golite062009
O-acyltransferase activity 1.33852311685118 bayes_pls_golite062009
carnitine O-palmitoyltransferase activity 1.22729402619659 bayes_pls_golite062009
O-palmitoyltransferase activity 1.22729402619659 bayes_pls_golite062009
transferase activity 1.08341671157927 bayes_pls_golite062009
carnitine O-acetyltransferase activity 1.00868366840715 bayes_pls_golite062009
binding 0.801074244553007 bayes_pls_golite062009
O-acetyltransferase activity 0.54660034926676 bayes_pls_golite062009
protein binding 0.00454070917775817 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle