YRC Public Data Repository - Protein Structure Prediction

Protein:	nas-22
Organism:	Caenorhabditis elegans
Length:	200 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-22.

Description	E-value	Query Range	Subject Range
gi\|47223677 - gi\|47223677\|emb\|CAF99286.1\| unnamed protein product [Tetraodon nigroviridis]	195.0	[0..33]	[199..95]
TLL1_XENLA - Tolloid-like protein 1 OS=Xenopus laevis GN=tll1 PE=1 SV=1	195.0	[0..21]	[199..119]
gi\|70571383, gi\|... - gi\|70571383\|dbj\|BAE06735.1\| Tolloid [Ciona intestinalis], gi\|118344032\|ref\|NP_001071840.1\| Tolloid p...	195.0	[0..40]	[199..340]
TLL1_CHICK - Tolloid-like protein 1 OS=Gallus gallus GN=TLL1 PE=2 SV=1	193.0	[0..21]	[199..120]
gi\|109076106 - gi\|109076106\|ref\|XP_001101883.1\| PREDICTED: similar to tolloid-like 1 [Macaca mulatta]	193.0	[0..17]	[199..119]
TLL1 - tolloid-like 1	192.0	[0..17]	[199..119]
gi\|114596743 - gi\|114596743\|ref\|XP_001150703.1\| PREDICTED: tolloid-like 1 isoform 2 [Pan troglodytes]	192.0	[0..17]	[199..119]
gi\|23268453 - gi\|23268453\|gb\|AAN11401.1\| metalloprotease 1 precursor [Ancylostoma ceylanicum]	192.0	[0..9]	[199..101]
TLL1_MOUSE - Tolloid-like protein 1 OS=Mus musculus GN=Tll1 PE=1 SV=1	192.0	[0..40]	[199..143]

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Predicted Domain #1

Region A:
Residues: [1-200]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSFFILLSI LQECYGKDIV ARIGGRNVAE KIGGARHRRQ VLIRGSDEER RHKWFNNTVH  60
   61 YYFYEENFDF TVKESILRAM ELISNHTCIK FSTEPSEKSI RMESDSTTIA CYAEIGQVRE 120
  121 NQLFSFNSDC YSAGVAVHEL IHSLGFIHAH QRSDRDQYLE FKKNLDELNQ TYQEQYKIWE 180
  181 YQEILVPYDV GSVMQYPNEE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.522879
Match:	1slmA
Description:	CRYSTAL STRUCTURE OF FIBROBLAST STROMELYSIN-1: THE C-TRUNCATED HUMAN PROENZYME
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.361128926739778	bayes_pls_golite062009
hydrolase activity	0.29183147920977	bayes_pls_golite062009
peptidase activity	0.23695590197447	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.0341081586881899	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: