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View Structure Prediction Details

Protein: phy-2
Organism: Caenorhabditis elegans
Length: 539 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for phy-2.

Description E-value Query
Range
Subject
Range
gi|50749316 - gi|50749316|ref|XP_421583.1| PREDICTED: similar to Prolyl 4-hydroxylase alpha-1 subunit (4-PH alpha-...
361.0 [0..1] [524..6]

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Predicted Domain #1
Region A:
Residues: [1-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRAVLLVCLL AGLAHADLFT AIADLQHMLG AEKDVTTIID QYIEAERARL DDLRRYAHEY  60
   61 VHRNAHAESV GPEFVTNPIN AYLLIKRLTT EWKKVENIML NNKASTFLKN ITDNRVRSEV 120
  121 KFPGEEDLSG AATALLRLQD TYSLDTLDLS NGIIGGEKVS NKLSGHDTFE VGRSAYNQKD 180
  181 YYHCLMWMQV ALVKIENENP PTIEEWEILE YLAYSLYQQG NVRRALSLTK RLAKIAPNHP 240
  241 RAKGNVKWYE DMLQGKDMVG DLPPIVNKRV EYDGIVERDA YEALCRG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.39794
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
procollagen-proline 4-dioxygenase activity 7.0422525853653 bayes_pls_golite062009
procollagen-proline dioxygenase activity 7.0422525853653 bayes_pls_golite062009
peptidyl-proline dioxygenase activity 7.0422525853653 bayes_pls_golite062009
peptidyl-proline 4-dioxygenase activity 7.0422525853653 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 5.01373106146099 bayes_pls_golite062009
binding 2.09193012129784 bayes_pls_golite062009
protein binding 1.52807685989528 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor 0.534990536504941 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [288-539]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EIPPVEPKWK NKLRCYLKRD KPFLKLAPIK VEILRFDPLA VLFKNVIHDS EIEVIKELAS  60
   61 PKLKRATVQN SKTGELEHAT YRISKSAWLK GDLDPVIDRV NRRIEDFTNL NQATSEELQV 120
  121 ANYGLGGHYD PHFDFARKEE KNAFKTLNTG NRIATVLFYM SQPERGGATV FNHLGTAVFP 180
  181 SKNDALFWYN LRRDGEGDLR TRHAACPVLL GVKWVSNKWI HEKGQEFTRP CGLEEEVQEN 240
  241 FIGDLSPYAN DP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.45
Match: 2hbtA
Description: No description for 2hbtA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle