YRC Public Data Repository - Protein Structure Prediction

Protein:	CE03743
Organism:	Caenorhabditis elegans
Length:	182 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE03743.

Description	E-value	Query Range	Subject Range
gi\|109506609, gi... - gi\|109507332\|ref\|XP_001056272.1\| PREDICTED: similar to Methionine aminopeptidase 2 (MetAP 2) (Peptid...	223.0	[0..11]	[179..293]
gi\|114646288 - gi\|114646288\|ref\|XP_509279.2\| PREDICTED: similar to Chain , Human Methionine Aminopeptidase 2 [Pan ...	222.0	[0..17]	[179..330]
METAP2 - methionyl aminopeptidase 2 gi\|55638671 - gi\|55638671\|ref\|XP_509279.1\| PREDICTED: methionyl aminopeptidase 2 [Pan troglodytes] gi\|208966762, gi... - gi\|208966762\|dbj\|BAG73395.1\| methionyl aminopeptidase 2 [synthetic construct], gi\|123995035\|gb\|ABM85...	222.0	[0..17]	[179..302]
gi\|109098246 - gi\|109098246\|ref\|XP_001107008.1\| PREDICTED: methionyl aminopeptidase 2 isoform 4 [Macaca mulatta]	221.0	[0..17]	[179..302]
gi\|57525368, gi\|... - gi\|57525368\|ref\|NP_001006233.1\| methionyl aminopeptidase 2 [Gallus gallus], gi\|53135475\|emb\|CAG32428...	221.0	[0..17]	[179..303]
gi\|73977621 - gi\|73977621\|ref\|XP_866154.1\| PREDICTED: similar to Methionine aminopeptidase 2 (MetAP 2) (Peptidase ...	221.0	[0..17]	[179..301]

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Predicted Domain #1

Region A:
Residues: [1-182]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILSDQNFLQ TQWKEPQTAQ SKNTESKCEF HGNSNEVKPI GSLNGQSIAQ CRIHTGKTVP  60
   61 IVKGGEQARM EENEIYAIET FGSTGKGYFH DDMETSHYMK NFELADEKIP LRLQKSKGLL 120
  121 KLIDKNFATL AFCRCWIDRL EETKYLMALK DRWMAMVGAC ILQSFAGKII GKRANLLLNL 180
  181 II

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.221849
Match:	1b6aA
Description:	HUMAN METHIONINE AMINOPEPTIDASE 2 COMPLEXED WITH TNP-470
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.835523092977445	bayes_pls_golite062009
transcription regulator activity	0.4843036104266	bayes_pls_golite062009
nucleic acid binding	0.37117756729668	bayes_pls_golite062009
DNA binding	0.3118855114645	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: