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View Structure Prediction Details

Protein: scc-1
Organism: Caenorhabditis elegans
Length: 645 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for scc-1.

Description E-value Query
Range
Subject
Range
gi|113681742, gi... - gi|94734316|emb|CAK10734.1| novel protein similar to vertebrate RAD21 homolog (S. pombe) (RAD21) [Da...
452.0 [0..1] [616..1]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFYAQFVLAK KGPLAKVWLA AHWEKKLTKA QIFETDVPQA IEEVIRPKVK MALRTVGHLL  60
   61 LGIVRIYSKK TRYLLADTNE AYQKMKINFR NGFSFEVDIP ENAEIE

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 62.455932
Match: PF04825.4
Description: No description for PF04825.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [107-399]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDFSNFIDKY NITVPEFHDA DYNEQLIMAN VSRREDITMK ETVNFNVEFN IDADFDGFGD  60
   61 EGESWQLDHL YGSVEPLSLR PTPQPESLME VERDRDVAAN GTEISRIDAD SVIFSEGPTR 120
  121 PNLIFDNQEG GNFMPEMNLK VENQTLENDG GVGPADMFSS MIHPVREHAV ADVQNDDGMD 180
  181 FDYQPFEPEN VEPSRPQSPE SFALEPLDVE HMEGRKKRQR KARKLIVDAE TMISNDAFRE 240
  241 QQEDFSDTMR VVEMAPPTRK MFNLCVSGDL QHLSREPGCK MFNRELLQRY RRC

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [400-499]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVTREFDLNY TMQELSDSSS FTPSMEAQAE PWEDLNLNED IQEDIQAQGP AVDEFFNDVR  60
   61 MDDDDDRQPA QEMDFGDNFD FPQEVEHQEC APIPIQSGFA 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [500-645]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GENKENEDAE DWSDPFGSSN SSRRGQLEAY GFGNTSTYKE DDGKWAKRAK HILKKVSADI  60
   61 ETSGQADFSS VTATAKNRKQ AAEQFYSLLT LAKSQAISVD QSEPYGEIVI RPGANFKEAC 120
  121 PLSSPKPMGL GNTMENSTMR TPMRPV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1w1wE
Description: Sc Smc1hd:Scc1-C complex, ATPgS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.04123976602801 bayes_pls_golite062009
transcription regulator activity 1.68038512705313 bayes_pls_golite062009
DNA binding 1.47502737137202 bayes_pls_golite062009
transcription factor activity 1.04009476736832 bayes_pls_golite062009
nucleic acid binding 0.802843603200847 bayes_pls_golite062009
protein binding 0.058151715836892 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle