YRC Public Data Repository - Protein Structure Prediction

Protein:	CE02530
Organism:	Caenorhabditis elegans
Length:	218 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE02530.

Description	E-value	Query Range	Subject Range
gi\|20093250, gi\|... - gi\|20093250\|ref\|NP_619325.1\| dTDP-glucose 4,6-dehydratase [Methanosarcina acetivorans C2A], gi\|19918...	179.0	[0..2]	[216..1]
gi\|72395839, gi\|... - gi\|73668677\|ref\|YP_304692.1\| dTDP-glucose 4,6-dehydratase [Methanosarcina barkeri str. Fusaro], gi\|7...	176.0	[0..2]	[216..1]
gi\|4240415 - gi\|4240415\|gb\|AAD13546.1\| NDP-hexose 4,6-dehydratase homolog [Streptomyces cyanogenus]	174.0	[0..1]	[211..1]
gi\|21227295, gi\|... - gi\|21227295\|ref\|NP_633217.1\| dTDP-glucose 4,6-dehydratase [Methanosarcina mazei Go1], gi\|20905647\|gb...	174.0	[0..2]	[216..1]
gi\|45658051, gi\|... - gi\|45658051\|ref\|YP_002137.1\| UDP-glucose 4-epimerase [Leptospira interrogans serovar Copenhageni str...	171.0	[0..2]	[212..1]
gi\|41205692 - gi\|41205692\|gb\|AAR99612.1\| dTDP-glucose 4,6-dehydratase [Geobacillus stearothermophilus]	170.0	[0..2]	[218..3]
gi\|24214280, gi\|... - gi\|24214280\|ref\|NP_711761.1\| UDP-glucose 4-epimerase [Leptospira interrogans serovar Lai str. 56601]...	170.0	[0..2]	[212..1]
gi\|7437238 - pir\|\|H69105 dTDP-glucose 4,6-dehydratase - Methanobacterium thermoautotrophicum (strain Delta H) gi\|15679777, gi\|... - gi\|2622920\|gb\|AAB86255.1\| dTDP-glucose 4,6-dehydratase [Methanothermobacter thermautotrophicus str. ...	169.0	[0..1]	[215..1]
gi\|18978160, gi\|... - gi\|18978160\|ref\|NP_579517.1\| NDP-sugar dehydratase or epimerase [Pyrococcus furiosus DSM 3638], gi\|1...	168.0	[0..1]	[211..1]
gi\|167726175, gi... - gi\|169235109\|ref\|YP_001688309.1\| nucleoside-diphosphate-sugar epimerase ( UDP-glucose 4-epimerase) [... gi\|15789397, gi\|... - pir\|\|A84167 UDP-glucose 4-epimerase [imported] - Halobacterium sp. NRC-1, gi\|15789397\|ref\|NP_279221....	167.0	[0..2]	[217..1]

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Predicted Domain #1

Region A:
Residues: [1-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSAFVVGAT GAVGSELVKL LAESTKFSKV VVLARRPVDG ATGDKLIQKT VDFDKLEENA  60
   61 EDIQGVDVAF CALGTTRGKS GADGFYKVDH DYVMSAAKMA KENGVKQFVL VSSVGADASS 120
  121 RFLYPKTKGE VEKEIGELNF EKFVIMRPGL IEAKRPEFRI GEFLGKIVTA PLGLFSNRFS 180
  181 SSATAIAQAM INATQTEETG NQIWNNSKIV EESKKYTA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.69897
Match:	2bkaA
Description:	CC3(TIP30)Crystal Strucure
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	1.95832530533882	bayes_pls_golite062009
DNA binding	1.94565956832747	bayes_pls_golite062009
nucleic acid binding	1.88939291163891	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
protein kinase activity	1.43163620422559	bayes_pls_golite062009
transporter activity	1.22995843907131	bayes_pls_golite062009
transcription factor activity	1.19425900841326	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.1558535124121	bayes_pls_golite062009
transcription activator activity	1.15481522446968	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.13055556901168	bayes_pls_golite062009
kinase activity	1.10917917260043	bayes_pls_golite062009
binding	0.982999356179965	bayes_pls_golite062009
transmembrane transporter activity	0.972811769368862	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.831597574657982	bayes_pls_golite062009
substrate-specific transporter activity	0.689869024389096	bayes_pls_golite062009
protein serine/threonine kinase activity	0.633682735649147	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.552977499662638	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.522485890380689	bayes_pls_golite062009
protein binding	0.507836099271263	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	0.235223624009216	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.225424035754398	bayes_pls_golite062009
ion transmembrane transporter activity	0.15567254780553	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: