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View Structure Prediction Details

Protein: nuo-4
Organism: Caenorhabditis elegans
Length: 436 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nuo-4.

Description E-value Query
Range
Subject
Range
gi|187026391, gi... - gi|39594034|emb|CAE70144.1| Hypothetical protein CBG16606 [Caenorhabditis briggsae], gi|187026391|em...
gi|157774871 - gi|157774871|ref|XP_001665501.1| hypothetical protein CBG16606 [Caenorhabditis briggsae AF16]
429.0 [0..1] [436..1]

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Predicted Domain #1
Region A:
Residues: [1-311]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGSMSKLGG LATGLLACSR SGALSNQVRG VVHKSLLRLP SEHPEPWDYK HNGFNYIDGL  60
   61 KDDTRSHFHQ NSKLIVVEGN IGSGKTTLAK QLADQLGFVH FPEFRMDDIL VDRYGNDLRN 120
  121 YYNKFPARYR LPDISMFYKN PSGELSAAMQ DRIFNCRFDQ YLNALAHILN TGQGVVLERT 180
  181 PHSDFVFANA MRDKNYIGHE YFKHYYFVRK NALPQLHFWP HLVVYLNTPT NKCLENIKRR 240
  241 GNTDEIATVD ERYLKTIEES YKDSLREYRN HSKILAYDWT KPGDTDAVVE DIERLDLDFF 300
  301 EWHSGDVMEE W

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.154902
Match: 4tmkA
Description: Thymidylate kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrogen ion transporting ATP synthase activity, rotational mechanism 3.59240819084968 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 3.32597131015894 bayes_pls_golite062009
substrate-specific transporter activity 3.27130158388246 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 3.20563367652813 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.1945674591238 bayes_pls_golite062009
oxidoreductase activity 3.16363151312976 bayes_pls_golite062009
ion transmembrane transporter activity 3.06875573889397 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 2.97411320405542 bayes_pls_golite062009
cation transmembrane transporter activity 2.90050421101998 bayes_pls_golite062009
binding 2.01755875920323 bayes_pls_golite062009
ribonucleotide binding 1.53142082854758 bayes_pls_golite062009
purine nucleotide binding 1.52938239070386 bayes_pls_golite062009
purine ribonucleotide binding 1.52887308780164 bayes_pls_golite062009
nucleotide binding 1.52746968836881 bayes_pls_golite062009
ATP binding 1.23942044024113 bayes_pls_golite062009
adenyl ribonucleotide binding 1.21044170258803 bayes_pls_golite062009
adenyl nucleotide binding 1.19481945569892 bayes_pls_golite062009
electron carrier activity 1.01221075506867 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
kinase activity 0.641541011250583 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.546796591575762 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.543610140926125 bayes_pls_golite062009
pyrophosphatase activity 0.540750418412449 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.517457589081898 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.40876498215632 bayes_pls_golite062009
4 iron, 4 sulfur cluster binding 0.160596246929241 bayes_pls_golite062009
protein binding 0.071010918255742 bayes_pls_golite062009
protein kinase activity 0.0646123847220056 bayes_pls_golite062009
nucleic acid binding 0.0636334376764289 bayes_pls_golite062009
hydrolase activity 0.0340518447528398 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [312-436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTIVDSVGWN GWRQYVTNKY DARMLAFDGI PKHEVGELYT NPRDTGHFLH VMRKEVLKSP  60
   61 YGYGYIAKNG DHQAGLNAWH TGHHLPEPWY EYYFREAYYD DLTSHETSLD LDSDSYDPDY 120
  121 VHHHH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle