YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|25361752
Organism: Caenorhabditis elegans
Length: 261 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25361752.

Description E-value Query
Range		 Subject
Range
ced-9 - Apoptosis regulator proteins, Bcl-2 family status:Confirmed UniProt:P41958 protein_id:CAA82573.2
 296.0 [0..1] [261..20]
CED9_CAEBR - Apoptosis regulator ced-9 OS=Caenorhabditis briggsae GN=ced-9 PE=3 SV=2
gi|157773681 - gi|157773681|ref|XP_001664906.1| hypothetical protein CBG24606 [Caenorhabditis briggsae AF16]
 250.0 [0..1] [261..20]
gi|32185285 - gi|32185285|gb|AAO64470.1| BCL-WEL [Rattus norvegicus]
 214.0 [0..28] [259..16]
gi|115607132 - gi|115607132|gb|ABJ16412.1| BCL2L2 [Felis catus]
 207.0 [0..60] [259..25]
B2CL2_MOUSE - Bcl-2-like protein 2 OS=Mus musculus GN=Bcl2l2 PE=1 SV=1
 206.0 [0..60] [259..9]
gi|40788933 - gi|40788933|dbj|BAA19666.2| KIAA0271 [Homo sapiens]
 205.0 [0..32] [259..3]
gi|61365749, gi|... - gi|61365749|gb|AAX42757.1| BCL2-like 2 [synthetic construct], gi|54695966|gb|AAV38355.1| BCL2-like 2...
 205.0 [0..60] [259..9]

Back

Predicted Domain #1
Region A:
Residues: [1-261] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATGEMKEFL GIKGTEPTDF GINSDAQDLP SPSRQASTRR MSIGESIDGK INDWEEPRLD  60
   61 IEGFVVDYFT HRIRQNGMEW FGAPGLPCGV QPEHEMMRVM GTIFEKKHAE NFETFCEQLL 120
  121 AVPRISFSLY QDVVRTVGNA QTDQCPMSYG RLIGLISFGG FVAAKMMESV ELQGQVRNLF 180
  181 VYTSLFIKTR IRNNWKEHNR SWDDFMTLGK QMKEDYERAE AEKVGRRKQN RRWSMIGAGV 240
  241 TAGAIGIVGV VVCGRMMFSL K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.0
Match: 2a5yA
Description: Structure of a CED-4/CED-9 complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.68532136060219 bayes_pls_golite062009
protein binding 1.27467799975395 bayes_pls_golite062009
BH3 domain binding 0.73278409982916 bayes_pls_golite062009
protein dimerization activity 0.717110763227649 bayes_pls_golite062009
BH domain binding 0.513227895728431 bayes_pls_golite062009
protein heterodimerization activity 0.0857017957923898 bayes_pls_golite062009
caspase inhibitor activity 0.0810673056766702 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle