YRC Public Data Repository - Protein Structure Prediction

Protein:	msw1
Organism:	Schizosaccharomyces pombe
Length:	361 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for msw1.

Description	E-value	Query Range	Subject Range
gi\|68057414, gi\|... - gi\|68249215\|ref\|YP_248327.1\| tryptophanyl-tRNA synthetase [Haemophilus influenzae 86-028NP], gi\|6805...	369.0	[0..11]	[358..3]
SYW_HAEIN - Tryptophanyl-tRNA synthetase OS=Haemophilus influenzae GN=trpS PE=3 SV=1 SYW_HAEIN - Tryptophan--tRNA ligase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=trp...	369.0	[0..11]	[358..1]
gi\|229809654, gi... - gi\|229847416\|ref\|ZP_04467516.1\| tryptophanyl-tRNA synthetase [Haemophilus influenzae 7P49H1], gi\|229... gi\|46133005 - gi\|46133005\|ref\|ZP_00156437.2\| COG0180: Tryptophanyl-tRNA synthetase [Haemophilus influenzae R2866] gi\|42628929 - gi\|42628929\|ref\|ZP_00154481.1\| COG0180: Tryptophanyl-tRNA synthetase [Haemophilus influenzae R2846]	368.0	[0..11]	[358..1]
SYW_PASMU - Tryptophanyl-tRNA synthetase OS=Pasteurella multocida GN=trpS PE=3 SV=1 SYW_PASMU - Tryptophan--tRNA ligase OS=Pasteurella multocida (strain Pm70) GN=trpS PE=3 SV=1	365.0	[0..11]	[358..1]
gi\|78212571, gi\|... - gi\|78212571\|ref\|YP_381350.1\| tryptophanyl-tRNA synthetase [Synechococcus sp. CC9605], gi\|78197030\|gb...	365.0	[0..11]	[358..1]
gi\|23467807, gi\|... - gi\|23467807\|ref\|ZP_00123385.1\| COG0180: Tryptophanyl-tRNA synthetase [Haemophilus somnus 129PT], gi\|...	365.0	[0..11]	[358..1]
gi\|170718585, gi... - gi\|53728306\|ref\|ZP_00133328.2\| COG0180: Tryptophanyl-tRNA synthetase [Haemophilus somnus 2336], gi\|1...	365.0	[0..11]	[358..1]
gi\|85060282, gi\|... - gi\|85060282\|ref\|YP_455984.1\| tryptophanyl-tRNA synthase [Sodalis glossinidius str. 'morsitans'], gi\|...	365.0	[0..11]	[358..1]
gi\|56685213, gi\|... - gi\|56750254\|ref\|YP_170955.1\| tryptophanyl-tRNA synthetase [Synechococcus elongatus PCC 6301], gi\|566... gi\|45512837 - ref\|ZP_00164403.1\| COG0180: Tryptophanyl-tRNA synthetase [Synechococcus elongatus PCC 7942]	362.0	[0..11]	[359..1]
gi\|81168998, gi\|... - gi\|81300117\|ref\|YP_400325.1\| tryptophanyl-tRNA synthetase [Synechococcus elongatus PCC 7942], gi\|811...	362.0	[0..11]	[359..19]

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Predicted Domain #1

Region A:
Residues: [1-361]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKLPKITSL LPHSRVVSGI QPTGIPHIGN YLGSLKQWVQ LQEEAARTPF SKCFFFVADL  60
   61 HALTVPQDPL KFRQARLDML AALLAIGINP QKSTLFFQSD VAQHSELAWL LACSTSMGQL 120
  121 NRMTQWKSKL HLHDHDDLSF LDASATSSTR FNLGLFSYPV LQAADILLYG ATHIPVGKDQ 180
  181 SQHVELTRSI ARSFNSSYKE KILTVPDIIL NSSSSIMALC QPEKKMSKSD INSKNYILLS 240
  241 DSTGEIRKKI SRAQTDNIKG ITYGDSNRPG INNLINIFAA ISDSTPSDIA QANASCSNAE 300
  301 FKEKVSSAII RCLQPISTSF NEWRQNRELL RDIAKKGAEE AVAEASSCMH KLKTLTGLSV 360
  361 Y

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	97.69897
Match:	1i6kA
Description:	Tryptophanyl-tRNA synthetase (TrpRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-oxygen bonds	7.16276509815667	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	7.16276509815667	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.13957775963187	bayes_pls_golite062009
ligase activity	6.11211476973434	bayes_pls_golite062009
tryptophan-tRNA ligase activity	5.34430928486195	bayes_pls_golite062009
glutamate-tRNA ligase activity	2.63681738794687	bayes_pls_golite062009
methionine-tRNA ligase activity	2.56893064485672	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
arginine-tRNA ligase activity	1.50161401062914	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
binding	0.535704308663141	bayes_pls_golite062009
nucleic acid binding	0.449504767632354	bayes_pls_golite062009
nucleotidyltransferase activity	0.2293846471193	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.126511747475258	bayes_pls_golite062009
glutamine-tRNA ligase activity	0.118292082006187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: