YRC Public Data Repository - Protein Structure Prediction

Protein:	zhf1
Organism:	Schizosaccharomyces pombe
Length:	387 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for zhf1.

Description	E-value	Query Range	Subject Range
gi\|11278580, gi\|... - gi\|1749680\|dbj\|BAA13897.1\| unnamed protein product [Schizosaccharomyces pombe], pir\|\|T43140 probable...	276.0	[0..1]	[387..1]
gi\|119613719, gi... - gi\|52351208\|ref\|NP_061183.2\| solute carrier family 30 (zinc transporter), member 10 [Homo sapiens], ... gi\|148921810, gi... - gi\|208967464\|dbj\|BAG73746.1\| solute carrier family 30, member 10 [synthetic construct], gi\|148921810... HGNC:25355\|MIM:6... - carrier family 30, member 10	242.0	[0..9]	[385..10]
gi\|55589382 - gi\|55589382\|ref\|XP_525065.1\| PREDICTED: solute carrier family 30 (zinc transporter), member 10 [Pan ...	241.0	[0..9]	[385..10]
gi\|109018230 - gi\|109018230\|ref\|XP_001103570.1\| PREDICTED: similar to solute carrier family 30 (zinc transporter), ...	240.0	[0..9]	[385..10]
gi\|157787032, gi... - gi\|157787032\|ref\|NP_001099455.1\| solute carrier family 30, member 10 [Rattus norvegicus], gi\|1490409...	237.0	[0..9]	[385..10]
gi\|157169784 - gi\|157169784\|gb\|AAI52751.1\| Solute carrier family 30, member 10 [synthetic construct] ZNT10_MOUSE - Zinc transporter 10 OS=Mus musculus GN=Slc30a10 PE=1 SV=1	236.0	[0..9]	[385..10]
gi\|76636955 - gi\|76636955\|ref\|XP_585153.2\| PREDICTED: similar to solute carrier family 30 (zinc transporter), memb...	234.0	[0..9]	[385..10]
gi\|171263 - gi\|171263\|gb\|AAA74884.1\| COT1 protein [Saccharomyces cerevisiae]	232.0	[0..5]	[374..5]

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Predicted Domain #1

Region A:
Residues: [1-108]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDLARQTRI ILLLGIDVTF FFIEIITGYA IDSLALIADS FHMLNDIVSL LVALWATRLA  60
   61 HSTSHEPKYT YGWQRAEILG ALSNGVFLIA LCMFIFMEAI ERFIEPPS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	5.07
Match:	2qfiA
Description:	No description for 2qfiA was found.

Predicted functions:

Term	Confidence	Notes
cation transmembrane transporter activity	6.20443686476571	bayes_pls_golite062009
ion transmembrane transporter activity	6.11479851651253	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	5.71521511150856	bayes_pls_golite062009
transporter activity	3.98293753989079	bayes_pls_golite062009
transmembrane transporter activity	3.88313530012213	bayes_pls_golite062009
substrate-specific transporter activity	3.86867537460555	bayes_pls_golite062009
cadmium ion transmembrane transporter activity	3.15489440737786	bayes_pls_golite062009
metal ion transmembrane transporter activity	2.61862894000527	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	2.19121021485065	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.14914871177232	bayes_pls_golite062009
cation channel activity	1.78793567733454	bayes_pls_golite062009
efflux transmembrane transporter activity	1.41612086977895	bayes_pls_golite062009
binding	1.28505954375411	bayes_pls_golite062009
ion channel activity	1.24140857317889	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	1.20401058605752	bayes_pls_golite062009
passive transmembrane transporter activity	1.19443885425411	bayes_pls_golite062009
channel activity	1.19443885425411	bayes_pls_golite062009
substrate-specific channel activity	1.19404477926718	bayes_pls_golite062009
active transmembrane transporter activity	0.475232131680683	bayes_pls_golite062009
protein binding	0.318355149027855	bayes_pls_golite062009
iron ion transmembrane transporter activity	0.186398867523746	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [109-387]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSNPTLMFFV GSLGLLSNFV GIFLFHDHGH DHPHTHTAQN YDFPEEDDIE SVLPSTIVHR  60
   61 CNTSQQEVSH THTQVADSAT ESSPLLSYTG NHNGAGTSKP VNNHGSIEQD APKQTKKRNL 120
  121 NMHGVFLHVL GDALGNIGVI SAALFIKYTD YSWRFLFDPC ISILLTFIIL FSAIPLCKSA 180
  181 ALILLQVAPQ SIKLDDVSNL INHLDGVESV HELHIWQLSD VKLIATVHVC VTLPDDKGES 240
  241 YTKLTTDIRN VLQSFGIYDV TIQPEFANHP LLCDQGSSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.221849
Match:	2qfiA
Description:	No description for 2qfiA was found.

Predicted functions:

Term	Confidence	Notes
cation transmembrane transporter activity	6.60087208506814	bayes_pls_golite062009
ion transmembrane transporter activity	6.49419690808578	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	6.066906606566	bayes_pls_golite062009
transporter activity	4.27173462293249	bayes_pls_golite062009
substrate-specific transporter activity	4.19993137135137	bayes_pls_golite062009
transmembrane transporter activity	4.18558383943492	bayes_pls_golite062009
cadmium ion transmembrane transporter activity	3.5658659940326	bayes_pls_golite062009
metal ion transmembrane transporter activity	2.68106285271045	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	2.32644140472297	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.19343183150052	bayes_pls_golite062009
efflux transmembrane transporter activity	2.11491587250012	bayes_pls_golite062009
cation channel activity	1.89531256510168	bayes_pls_golite062009
ion channel activity	1.33777369753101	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	1.31663166812163	bayes_pls_golite062009
substrate-specific channel activity	1.28221434614717	bayes_pls_golite062009
passive transmembrane transporter activity	1.27960450391272	bayes_pls_golite062009
channel activity	1.27960450391272	bayes_pls_golite062009
binding	1.27456652114636	bayes_pls_golite062009
active transmembrane transporter activity	0.490905558612378	bayes_pls_golite062009
iron ion transmembrane transporter activity	0.376948884172728	bayes_pls_golite062009
protein binding	0.311357063667067	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: