YRC Public Data Repository - Protein Structure Prediction

Protein:	tsf1
Organism:	Schizosaccharomyces pombe
Length:	299 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tsf1.

Description	E-value	Query Range	Subject Range
EFTS_AQUAE - Elongation factor Ts OS=Aquifex aeolicus (strain VF5) GN=tsf PE=3 SV=1 EFTS_AQUAE - Elongation factor Ts OS=Aquifex aeolicus GN=tsf PE=3 SV=1	248.0	[0..30]	[287..3]
EFTS_MOUSE - Elongation factor Ts, mitochondrial OS=Mus musculus GN=Tsfm PE=1 SV=1	247.0	[0..11]	[297..32]
gi\|25299529 - gi\|25299529\|pir\|\|F97526 elongation factor TS (ef-ts) [imported] - Agrobacterium tumefaciens (strain ... gi\|15156441, gi\|... - gi\|15888701\|ref\|NP_354382.1\| elongation factor Ts [Agrobacterium tumefaciens str. C58], gi\|15156441\|...	246.0	[0..6]	[287..49]
gi\|114704875, gi... - gi\|114704875\|ref\|ZP_01437783.1\| translation elongation factor Ts protein [Fulvimarina pelagi HTCC250...	244.0	[0..29]	[287..16]
TSFM - Ts translation elongation factor, mitochondrial	243.0	[0..10]	[294..32]
gi\|109097525 - gi\|109097525\|ref\|XP_001116504.1\| PREDICTED: Ts translation elongation factor, mitochondrial [Macaca ...	243.0	[0..10]	[294..32]
gi\|133727060, gi... - gi\|254872766\|ref\|ZP_05245476.1\| elongation factor Ts [Listeria monocytogenes FSL N1-017], gi\|1531673... EFTS_LISMC - Elongation factor Ts OS=Listeria monocytogenes serotype 4b (strain Clip81459) GN=tsf PE=3 SV=1 EFTS_LISMH - Elongation factor Ts OS=Listeria monocytogenes serotype 4a (strain HCC23) GN=tsf PE=3 SV=1 gi\|254852281 - gi\|254852281\|ref\|ZP_05241629.1\| elongation factor Ts [Listeria monocytogenes FSL R2-503] EFTS_LISMC - Elongation factor Ts OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=tsf PE=3 SV=1 gi\|254824282 - gi\|254824282\|ref\|ZP_05229283.1\| elongation factor Ts [Listeria monocytogenes FSL J1-194] gi\|255521679 - gi\|255521679\|ref\|ZP_05388916.1\| elongation factor Ts [Listeria monocytogenes FSL J1-175] gi\|254992981 - gi\|254992981\|ref\|ZP_05275171.1\| elongation factor Ts [Listeria monocytogenes FSL J2-064] EFTS_LISMF - Elongation factor Ts OS=Listeria monocytogenes serotype 4b (strain F2365) GN=tsf PE=3 SV=1 gi\|47093766, gi\|... - gi\|47093766\|ref\|ZP_00231515.1\| translation elongation factor Ts [Listeria monocytogenes str. 4b H785...	242.0	[0..29]	[290..1]
EFTS_BACSK - Elongation factor Ts OS=Bacillus clausii (strain KSM-K16) GN=tsf PE=3 SV=1	242.0	[0..30]	[284..1]

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Predicted Domain #1

Region A:
Residues: [1-299]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFQRRLHFH QFFGKTRVTG SLSRQWYSKL PSKLADIKKL RSETNASMDL VKQSVEEAGV  60
   61 GNLELAREIL KKKIVQRGGK LAEKSKNRTA KEGWIIQCIS EDGRKAVMAE INCESDFVAQ 120
  121 TTPFQDLARR IASTFLHYLP TNHSSYSVEA TLKNEILKHQ AYVSKNHEAN EKDVSSNVSL 180
  181 EEEIVKMTSF TGEKVQVQRL HCMNARVPST AIGIFSHGAK QSSPLQQLGR IGSMVQINSD 240
  241 LSTRKGLSNQ IAKEIVAQDP SSTSELLSFR SLVDSEKTIK DVLGQSTILE WVRWERGGN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.154902
Match:	1xb2B
Description:	Crystal Structure of Bos taurus mitochondrial Elongation Factor Tu/Ts Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation elongation factor activity	2.25105802083938	bayes_pls_golite062009
binding	1.38178580050618	bayes_pls_golite062009
small conjugating protein binding	0.985424343145381	bayes_pls_golite062009
ubiquitin binding	0.83381750627184	bayes_pls_golite062009
nucleic acid binding	0.615703185217616	bayes_pls_golite062009
transcription regulator activity	0.422128973505256	bayes_pls_golite062009
protein binding	0.378700375319735	bayes_pls_golite062009
DNA binding	0.262676519883369	bayes_pls_golite062009
catalytic activity	0.25774924710417	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: