YRC Public Data Repository - Protein Structure Prediction

Protein:	swc2
Organism:	Schizosaccharomyces pombe
Length:	316 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for swc2.

Description	E-value	Query Range	Subject Range
gi\|40253658, gi\|... - gi\|50941921\|ref\|XP_480488.1\| putative stress responsive gene 6 protein, Srg6 [Oryza sativa (japonica...	173.0	[0..11]	[315..15]
gi\|12054307, gi\|... - gi\|12054307\|emb\|CAC20595.1\| stress responsive gene 6, Srg6 [Hordeum vulgare subsp. vulgare], gi\|1205...	173.0	[0..10]	[315..16]
gi\|25408505, gi\|... - gi\|4415919\|gb\|AAD20150.1\| hypothetical protein [Arabidopsis thaliana], pir\|\|B84784 hypothetical prot...	172.0	[0..11]	[302..14]
gi\|109467177, gi... - gi\|34858037\|ref\|XP_227428.2\| PREDICTED: similar to Vacuolar protein sorting protein 72 homolog (Prot...	171.0	[0..6]	[304..2]
gi\|57098805 - gi\|57098805\|ref\|XP_533052.1\| PREDICTED: similar to YL-1 protein (Transcription factor-like 1) [Canis...	170.0	[0..6]	[304..2]
gi\|61368727, gi\|... - gi\|61368727\|gb\|AAX43227.1\| transcription factor-like 1 [synthetic construct], gi\|54695580\|gb\|AAV3816...	167.0	[0..6]	[304..2]
gi\|61358634, gi\|... - gi\|61358634\|gb\|AAX41598.1\| transcription factor-like 1 [synthetic construct], gi\|61358625\|gb\|AAX4159... VPS72 - vacuolar protein sorting 72 homolog (S. cerevisiae)	166.0	[0..6]	[304..2]
VPS72_PONPY - Vacuolar protein sorting-associated protein 72 homolog - Pongo pygmaeus (Orangutan) VPS72_PONAB - Vacuolar protein sorting-associated protein 72 homolog OS=Pongo abelii GN=VPS72 PE=2 SV=1	165.0	[0..6]	[304..2]
gi\|109016140 - gi\|109016140\|ref\|XP_001104866.1\| PREDICTED: transcription factor-like 1 [Macaca mulatta] gi\|163781015 - gi\|163781015\|gb\|ABY40791.1\| vacuolar protein sorting 72 homolog (predicted) [Papio anubis]	165.0	[0..6]	[304..2]

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Predicted Domain #1

Region A:
Residues: [1-77]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATESLVAG RTRRANAGNK MRELLEKEHL RMTQQNAEIE KEDEEYNIEE EEEAERDIEI  60
   61 SSESSDEEAE LKKLEEE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [78-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEEVEKILRD EERIKKRKIQ KNRAANLQRT LQPPKRPTPS AASEVPKKKY KKIKVDPSAR  60
   61 RTSSRMHTVL MAQSTETRLQ EAKPRRKYTV SASANRQKGT MTQQQRFEEA AKTEAQNLSS 120
  121 LRNYVHLEEQ RRLRLKRNAA KHRQLRE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.09691
Match:	1dg3A
Description:	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [225-316]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PILKFISKTI STEDGREASN YYVAPLEHPL CHSAPPLQMP QHRAVECVIT GKPAIYLDPV  60
   61 TQLPISNVQA FQQVREVYNQ RYSWSAMLNL FH

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.17
Match:	1x4sA
Description:	Solution structure of zinc finger HIT domain in protein FON
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.48298025894013	bayes_pls_golite062009
nucleic acid binding	2.27695396544623	bayes_pls_golite062009
DNA binding	2.13220564234684	bayes_pls_golite062009
binding	2.04387193075129	bayes_pls_golite062009
transcription activator activity	0.570282420961288	bayes_pls_golite062009
protein binding	0.520486355666439	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.512364998565023	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: