YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC244.02c
Organism:	Schizosaccharomyces pombe
Length:	488 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC244.02c.

Description	E-value	Query Range	Subject Range
gi\|91079875 - gi\|91079875\|ref\|XP_967579.1\| PREDICTED: similar to CG10392-PB, isoform B [Tribolium castaneum]	305.0	[0..23]	[464..164]
gi\|56967372, gi\|... - gi\|62821820\|ref\|NP_001017359.1\| O-linked N-acetylglucosamine transferase isoform 1 [Danio rerio], gi...	298.0	[0..23]	[464..27]
gi\|76659271 - gi\|76659271\|ref\|XP_884992.1\| PREDICTED: similar to O-linked GlcNAc transferase isoform 1 isoform 7 [...	298.0	[0..23]	[464..27]
gi\|74007684 - gi\|74007684\|ref\|XP_858918.1\| PREDICTED: similar to O-linked GlcNAc transferase isoform 1 isoform 11 ...	296.0	[0..23]	[464..27]
gi\|5052534 - gi\|5052534\|gb\|AAD38597.1\|AF145622_1 BcDNA.GH04245 [Drosophila melanogaster]	296.0	[0..23]	[464..56]
gi\|66793439, gi\|... - gi\|66793439\|ref\|NP_001019747.1\| UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase [Xe...	296.0	[0..23]	[464..17]

Back

Predicted Domain #1

Region A:
Residues: [1-408]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEKVQYYME QSVPELEDLL EKNIFNRDEI NNIIKTRRVF EEKLARRQVK LNDFLSYIQY  60
   61 EINLETLRAK RHKRLNITGK ITISDYAGPR KVLFLFLRAT NKFFGDVTLW LDYIHYAQKI 120
  121 KAVNIVGKIC VAALQKHPNN AELWVVACDH EFSINANVSA ARALMNRALR LNQENPVIWA 180
  181 AYFRLELSYM TKLFARSQIL TGNISSKTEN ITNGVSEDTI GSLSSDTIQL PMVSMEEFLG 240
  241 SSSSEVRKND SDLNISDDIG NISSKEQQTQ KFANVLLQII LNSRKNLSLQ NYVGFFVSVL 300
  301 DALFECFDVP VVQYMYQENI IGICNEHFEH FKNESGEIYG VLLHRWCFLE IFIKLRGAYP 360
  361 SNDSGISGKG IFGLKKNDPR ITSMVLTDPG FVDDLQAIVE KYQSISSD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.39794
Match:	1w3bA
Description:	The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.12690485191789	bayes_pls_golite062009
RNA binding	2.0770703064779	bayes_pls_golite062009
protein binding	1.39668540998298	bayes_pls_golite062009
transcription regulator activity	1.26149030245805	bayes_pls_golite062009
DNA binding	0.9531600253493	bayes_pls_golite062009
nucleic acid binding	0.93037889019021	bayes_pls_golite062009
transcription factor activity	0.374364600772076	bayes_pls_golite062009
ligase activity	0.102007806594868	bayes_pls_golite062009
signal sequence binding	0.0529781042891342	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [409-488]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQIPFKTKKI FYSFFVKTLH AISSSSAAES SIALALHMLV INAFQSMEKL KILTFDDSLQ  60
   61 EIYKEAQIQS GTFMSNATLS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.853	0.006	small nucleolar ribonucleoprotein complex	a.4.9	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: