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View Structure Prediction Details

Protein: rpn2
Organism: Schizosaccharomyces pombe
Length: 965 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rpn2.

Description E-value Query
Range		 Subject
Range
gi|76610889 - gi|76610889|ref|XP_886237.1| PREDICTED: similar to proteasome 26S non-ATPase subunit 1 isoform 16 [B...
 725.0 [0..11] [940..1]
gi|109101399 - gi|109101399|ref|XP_001113035.1| PREDICTED: similar to proteasome 26S non-ATPase subunit 1 [Macaca m...
 723.0 [0..11] [940..1]
gi|147905374, gi... - gi|71682400|gb|AAI00173.1| MGC114631 protein [Xenopus laevis], gi|147905374|ref|NP_001089647.1| hypo...
 723.0 [0..11] [940..1]
gi|55732382 - gi|55732382|emb|CAH92892.1| hypothetical protein [Pongo abelii]
PSMD1_PONAB - 26S proteasome non-ATPase regulatory subunit 1 OS=Pongo abelii GN=PSMD1 PE=2 SV=1
ENSPTRT00000024140 - null
 723.0 [0..11] [940..1]
PSD, PSMD1 - proteasome (prosome, macropain) 26S subunit, non-ATPase, 1, pleckstrin and Sec7 domain containing
 723.0 [0..11] [940..1]
PSMD1_MOUSE - 26S proteasome non-ATPase regulatory subunit 1 OS=Mus musculus GN=Psmd1 PE=1 SV=1
 722.0 [0..11] [940..1]
PSMD1_RAT - 26S proteasome non-ATPase regulatory subunit 1 OS=Rattus norvegicus GN=Psmd1 PE=1 SV=1
 721.0 [0..11] [940..1]
PSD1A_ARATH - 26S proteasome non-ATPase regulatory subunit 1 homolog A OS=Arabidopsis thaliana GN=RPN2A PE=1 SV=1
 719.0 [0..8] [959..2]

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Predicted Domain #1
Region A:
Residues: [1-722] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMVYSDNTS IITSAGGLMA LLDEQERELQ VHALLKIYEF IDQLWPEISD DVTKIEVMYE  60
   61 DHSFPERELA ALVVSKVYYY LGEYDEALLF ALSSGPKFLH DKNSDYKETL IFKCIDMFIH 120
  121 KSAELYKNPK ADPLDERLSG VVEGIFQKCY AKNEWRHVLG IAIEAHRLDI IEYILNADKE 180
  181 TDLKPYVLEL AMTVVLDIEF RNRLLRLLLS SFLTETEPDY FSVGKCVVHL NDASVAAKLL 240
  241 MKLSSQNDDK SLLTAYQLAF DLEDSAPQEF LNSVMDLLPS PSVANSEEDA NADSKKEDSS 300
  301 PCGYIIRILS GEQTVKYDRE FLYAHNNTDM LILNRTKDSL EARNSVFHNA VTFANAFMNF 360
  361 GTSSDSFFRD NLSWLSKANN WSKFTATAAL GVIHRGYYNQ AMNILRPYLP EEDAPSSSTY 420
  421 SEGGAFYAMG LIHANHGRGV TEYLREQLKH TEDEIVQYGL LLGIGLTGMA SRDETLYESV 480
  481 KTILFNDNAV AGSAAGISMG LIMLGTASSA AIDEMLQYAH ETQHEKIIRG LGIGIALIVY 540
  541 GRQQEADGII KELNNDLDPT LRYAGMFATA LAYCGTSNSK IVRDVLHISV SDVNDDVRRA 600
  601 AVCALGFICF KDPNALISTV ELLVDSYNPH VRYGSAIALG IACANSGSNA ALDLLSRLVE 660
  661 DATDFVRQGA MIAQAMILTQ HNDQLNSKVS GIRKHFEQVI NEKHEDALAK LGATLAQGII 720
  721 DA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.522879
Match: 1qbkB
Description: Karyopherin beta2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.86831493830281 bayes_pls_golite062009
hydrolase activity 2.5894939457048 bayes_pls_golite062009
protein binding 1.63705839411934 bayes_pls_golite062009
cytoskeletal protein binding 1.23804310697631 bayes_pls_golite062009
nucleic acid binding 1.13208464017585 bayes_pls_golite062009
structural molecule activity 0.440301695287117 bayes_pls_golite062009
actin binding 0.360199499297314 bayes_pls_golite062009
DNA binding 0.171056781378569 bayes_pls_golite062009
transcription regulator activity 0.123389318446902 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [723-855] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGRNVTIALQ TATGSLKLSA IVGLTVFLQY WYWFPLTHFM SLSFSPTALI GLDKNLNAPK  60
   61 FSFISNVRPK LFAYPPKSVQ PTAKTVQKVE TAVLSTTVKA QARAKRAERE KASKGSNDDE 120
  121 MKIDKKTTEE KEA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.154902
Match: 2bkuB
Description: Kap95p:RanGTP complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [856-965] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPMEMDEEKS QDISINGNSK KEEPKSETLE NFTRVVPAQL PYISFNLNGR YYPVRKFTGG  60
   61 VLMLIDRESD KAPDLIELNR DAVPASADTE PGEQEASPPE DFEYPFDDDD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle