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View Structure Prediction Details

Protein: SPBC3B9.01
Organism: Schizosaccharomyces pombe
Length: 287 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC3B9.01.

Description E-value Query
Range
Subject
Range
IMA1_MOUSE - Importin subunit alpha-1 OS=Mus musculus GN=Kpna2 PE=1 SV=2
gi|53733645 - gb|AAH83956.1| Unknown (protein for MGC:97971) [Xenopus laevis]
213.0 [0..2] [285..71]
gi|59800319, gi|... - gi|59800319|gb|AAX07453.1| karyopherin alpha 2 [Rattus norvegicus], gi|58477719|gb|AAH89787.1| Karyo...
212.0 [0..2] [285..71]
gi|73965251 - gi|73965251|ref|XP_850677.1| PREDICTED: similar to Importin alpha-2 subunit (Karyopherin alpha-2 sub...
212.0 [0..2] [285..71]
gi|74354742, gi|... - gi|77735853|ref|NP_001029621.1| karyopherin alpha 2 (RAG cohort 1, importin alpha 1) [Bos taurus], g...
210.0 [0..2] [285..71]
gi|67969843 - gi|67969843|dbj|BAE01269.1| unnamed protein product [Macaca fascicularis]
209.0 [0..2] [285..71]

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Predicted Domain #1
Region A:
Residues: [1-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKLLAFSTQ LQAQGNSSNS PPDPKDLDPS VLDHIFGANP ADEMRKAMDA IEDPSVPLDQ  60
   61 KEIAFDNLEM LVEHIDNANN LVPLQLWPRL LKQLESPEST LRRLAAWTIA TAVQNNPKSQ 120
  121 QALIENDGLK ILFGALKKED SDETKNKVLY AITSELKLNE AGIALLDKIP NSWEMLIEIL 180
  181 ELKHSVMTKR VIFFFYALLI QEDKSKQIIL QKAHEFQIPE KVYQFSLEHS VDEDCVTKSL 240
  241 HTLYLFQKNK VSVANTNELL KSLVQFKSEF PEIFTVDEWK AFHEALE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.0
Match: 1q1sC
Description: Mouse Importin alpha- phosphorylated SV40 CN peptide complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.47395644967726 bayes_pls_golite062009
nucleic acid binding 1.72695422276859 bayes_pls_golite062009
protein binding 1.04044934052933 bayes_pls_golite062009
translation regulator activity 0.82193201542158 bayes_pls_golite062009
transcription regulator activity 0.821718728559452 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.803700928110921 bayes_pls_golite062009
DNA binding 0.797151158461249 bayes_pls_golite062009
translation initiation factor activity 0.52296625430866 bayes_pls_golite062009
structural molecule activity 0.444796267478425 bayes_pls_golite062009
RNA binding 0.40024158562931 bayes_pls_golite062009
transcription factor activity 0.123371336741999 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle