YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAPB1A10.11c
Organism:	Schizosaccharomyces pombe
Length:	526 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAPB1A10.11c.

Description	E-value	Query Range	Subject Range
gi\|27262332 - gi\|27262332\|gb\|AAN87447.1\| Glutamyl-tRNA synthetase [Heliobacillus mobilis]	375.0	[0..34]	[516..4]
SYE_DESRM - Glutamate--tRNA ligase OS=Desulfotomaculum reducens (strain MI-1) GN=gltX PE=3 SV=1	374.0	[0..32]	[513..1]
SYE_HAEDU - Glutamyl-tRNA synthetase OS=Haemophilus ducreyi GN=gltX PE=3 SV=1 SYE_HAEDU - Glutamate--tRNA ligase OS=Haemophilus ducreyi (strain 35000HP / ATCC 700724) GN=gltX PE=3 SV=1	371.0	[0..20]	[519..4]
gi\|68547519, gi\|... - gi\|68547519\|ref\|ZP_00587054.1\| Glutamyl-tRNA synthetase bacterial/mitochondrial [Shewanella amazonen...	371.0	[0..32]	[524..1]
SYE_PASMU - Glutamate--tRNA ligase OS=Pasteurella multocida (strain Pm70) GN=gltX PE=3 SV=1 SYE_PASMU - Glutamyl-tRNA synthetase OS=Pasteurella multocida GN=gltX PE=3 SV=1	370.0	[0..18]	[516..2]
gi\|219666464, gi... - gi\|68209573\|ref\|ZP_00561540.1\| Glutamyl-tRNA synthetase bacterial/mitochondrial [Desulfitobacterium ... SYE_DESHY - Glutamate--tRNA ligase OS=Desulfitobacterium hafniense (strain Y51) GN=gltX PE=3 SV=1	369.0	[0..36]	[517..4]
SYE1_CALS8 - Glutamate--tRNA ligase 1 OS=Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8...	368.0	[0..32]	[509..1]
SYE_PECAS - Glutamate--tRNA ligase OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) GN=gltX PE=3... SYE_ERWCT - Glutamate--tRNA ligase OS=Erwinia carotovora subsp. atroseptica GN=gltX PE=3 SV=1	368.0	[0..32]	[517..1]
SYE_SHESR - Glutamate--tRNA ligase OS=Shewanella sp. (strain MR-7) GN=gltX PE=3 SV=1 SYE_SHESA - Glutamate--tRNA ligase OS=Shewanella sp. (strain ANA-3) GN=gltX PE=3 SV=1	367.0	[0..32]	[514..1]
SYE_YERPY - Glutamate--tRNA ligase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=gltX PE=3 SV=1 SYE_YERP3 - Glutamate--tRNA ligase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=gltX PE=3 S...	367.0	[0..32]	[517..1]

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Predicted Domain #1

Region A:
Residues: [1-526]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSYTSCAKL ICSRYIVSKI SFYSLKRCNS TAVVRTRFAP SPTGFLHLGS LRTALFNYLW  60
   61 AKKSNGKFIL RLEDTDQKRK VTGSDLEIYK VLKQFNLQWD EGPIVGGPYG PYEQSSRLQI 120
  121 YQKYAQHLIE TGRAYVSYSV PIATTKIDSS TKYHEISIDD LTDAQRKLYK SKKFPYVVRF 180
  181 RMKEPSPFTD LVYGKIAIKS DSREIEESNN FVILKSDGFP TYHFANVVDD HLMHITHVIR 240
  241 GEEWVPSTIK HIQLYEAFGW KPPKFAHLPL LVNPDGSKLS KRQNDAHVSS LLQEGFLPEA 300
  301 ILNFIALMGW SSRQKSDFLP MKELIDLFSI DKLTKSSSIV AFEKLYFLNK NYLRRAISDV 360
  361 NRLDELIELV QPRLIQKFSH SSRSHDKSYT KKLLLLLKNK VHTIKEFEKI VFYFYEASDL 420
  421 QQIRSLVSSL ITVEELPKIL TTILNKFETI EWNTHEIQIS LKEIAMEHQM PLKKIQSLLR 480
  481 YGLCGNLPGG GISDTISLLG KETVKSRLER LLLSLKHELP KRSCIV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	95.0
Match:	1j09A
Description:	C-terminal domain of glutamyl-tRNA synthetase (GluRS); Glutamyl-tRNA synthetase (GluRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glutamate-tRNA ligase activity	11.5182978121348	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.16276509815667	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	7.16276509815667	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.13957775963187	bayes_pls_golite062009
ligase activity	6.11211476973434	bayes_pls_golite062009
methionine-tRNA ligase activity	2.56893064485672	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
arginine-tRNA ligase activity	1.50161401062914	bayes_pls_golite062009
tryptophan-tRNA ligase activity	1.14187887833901	bayes_pls_golite062009
nucleotidyltransferase activity	1.06535308346284	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
binding	0.485102284225571	bayes_pls_golite062009
nucleic acid binding	0.449504767632354	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.126511747475258	bayes_pls_golite062009
glutamine-tRNA ligase activity	0.118292082006187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: