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View Structure Prediction Details

Protein: SPBC2G2.16
Organism: Schizosaccharomyces pombe
Length: 412 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC2G2.16.

Description E-value Query
Range		 Subject
Range
gi|51558025 - gi|51558025|gb|AAU06585.1| mannosephosphate isomerase [Aspergillus fumigatus]
 461.0 [0..1] [412..6]
MPI_ASPFU, MANA_... - Mannose-6-phosphate isomerase OS=Aspergillus fumigatus GN=pmi1 PE=2 SV=2, Mannose-6-phosphate isomer...
gi|159131453 - gi|159131453|gb|EDP56566.1| mannose-6-phosphate isomerase, class I [Aspergillus fumigatus A1163]
MPI_ASPFU - Mannose-6-phosphate isomerase OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / F...
 461.0 [0..1] [412..6]
MPI_BOVIN - Mannose-6-phosphate isomerase OS=Bos taurus GN=MPI PE=2 SV=3
 458.0 [0..1] [410..6]
gi|14290579 - gi|14290579|gb|AAH09068.1| Mannose phosphate isomerase [Mus musculus]
 456.0 [0..1] [410..6]
MPI_MACFA - Mannose-6-phosphate isomerase OS=Macaca fascicularis GN=MPI PE=2 SV=3
 454.0 [0..1] [410..6]
MPI_RAT - Mannose-6-phosphate isomerase OS=Rattus norvegicus GN=Mpi PE=2 SV=1
 453.0 [0..1] [410..6]
MANA_NEUCR, MPI_... - Mannose-6-phosphate isomerase OS=Neurospora crassa GN=103E1.170 PE=3 SV=1, Mannose-6-phosphate isome...
MPI_NEUCR - Mannose-6-phosphate isomerase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DS...
 453.0 [0..1] [410..6]
MPI - mannose phosphate isomerase
 453.0 [0..1] [410..6]
gi|114658120 - gi|114658120|ref|XP_001140578.1| PREDICTED: mannose-6- phosphate isomerase isoform 11 [Pan troglodyt...
 452.0 [0..1] [410..6]

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Predicted Domain #1
Region A:
Residues: [1-412] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYRLKCDVKS YGWGKVGHES LAAKLAEAGY GFEVDPNTPY AELWMGSHPS GPSFVMQTGK  60
   61 PLSELLTPET VGEKVYKKYG KQLPFLFKVL SINKVLSIQA HPDKPLGKQL HKTNPKEYKD 120
  121 DNHKPEMAVA LTEFDALCGF RPVKQIEQFL DSIAPLREFV GEEAVRQFKG TVKQDERKAL 180
  181 ETLFNELMHK DEKRIQEFTP QLVQLAKSDA NNFGGTEYGG KAFSDLIIHL NSQFPDDIGL 240
  241 FVTPFLNYVR LHPGEAVFLR ALDPHAYVSG NIIECMAASD NVIRLGFTPK FKDIETLVNN 300
  301 LTYQTADAKS QLTQPVPFAK ACGSGKTLLY DPPIEEFSIL QTKVSPGQKQ CIRGINGPSI 360
  361 LLVTEGSGIL NGDKGDVASI SPGFVYFISA NFPLTISATS EPVVVYQAFC EI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 122.0
Match: 1pmiA
Description: HUMAN RANTES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 1.86690435826277 bayes_pls_golite062009
nucleic acid binding 1.64913898350018 bayes_pls_golite062009
DNA binding 1.57178406956273 bayes_pls_golite062009
binding 1.54596514444405 bayes_pls_golite062009
transcription factor activity 0.937392765385803 bayes_pls_golite062009
intramolecular oxidoreductase activity 0.8581504516071 bayes_pls_golite062009
catalytic activity 0.401988496917198 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 0.353173877157675 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses 0.348782780143283 bayes_pls_golite062009
protein binding 0.110960530780648 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle