YRC Public Data Repository - Protein Structure Prediction

Protein:	sen54
Organism:	Schizosaccharomyces pombe
Length:	384 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sen54.

Description	E-value	Query Range	Subject Range
gi\|46109196, gi\|... - gi\|46109196\|ref\|XP_381656.1\| hypothetical protein FG01480.1 [Gibberella zeae PH-1], gi\|42546022\|gb\|E...	380.0	[0..1]	[372..1]
SE54_ASHGO, SEN5... - tRNA-splicing endonuclease subunit SEN54 OS=Ashbya gossypii GN=SEN54 PE=3 SV=1, (Q74ZJ5) tRNA-splici... SEN54_ASHGO - tRNA-splicing endonuclease subunit SEN54 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9...	379.0	[0..15]	[375..16]
gi\|67523987, gi\|... - gi\|67523987\|ref\|XP_660053.1\| hypothetical protein AN2449.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	351.0	[0..1]	[347..4]
gi\|83768654 - gi\|83768654\|dbj\|BAE58791.1\| unnamed protein product [Aspergillus oryzae] gi\|169772649 - gi\|169772649\|ref\|XP_001820793.1\| hypothetical protein [Aspergillus oryzae RIB40]	300.0	[0..1]	[373..1]
SE54_NEUCR, SEN5... - Probable tRNA-splicing endonuclease subunit sen-54 OS=Neurospora crassa GN=sen-54 PE=3 SV=1, (Q7SC91... SEN54_NEUCR - Probable tRNA-splicing endonuclease subunit sen-54 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23...	298.0	[0..1]	[369..3]
gi\|46438274, gi\|... - gi\|68478667\|ref\|XP_716602.1\| potential tRNA splicing endonuclease subunit [Candida albicans SC5314],... orf19.7361 - orf19.7361 CGDID:CAL0004706 Assembly 19, Contig19-2513 (30399, 31817) CDS, translated using codon ta...	295.0	[0..14]	[360..39]
gi\|114195627, gi... - gi\|115388075\|ref\|XP_001211543.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	294.0	[0..16]	[384..20]
gi\|70992187, gi\|... - gi\|70992187\|ref\|XP_750942.1\| tRNA splicing endonuclease subunit (Sen54) [Aspergillus fumigatus Af293...	284.0	[0..1]	[373..4]
SEN54 - Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p SEN54_YEAST - tRNA-splicing endonuclease subunit SEN54 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...	270.0	[0..2]	[316..9]
gi\|90298873, gi\|... - gi\|90298873\|gb\|EAS28504.1\| hypothetical protein CIMG_09708 [Coccidioides immitis RS], gi\|119175869\|r...	252.0	[0..16]	[364..22]

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Predicted Domain #1

Region A:
Residues: [1-99]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAQDEDNPF TNLETTVDVT EEIQDWRFLS NVEKDQGTYT IPKRGQKDFE PDGTNKQHSA  60
   61 LDLSRKAMFD ALSVERLISA KHAIIATWNA QNGMSCVEK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [100-254]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHGPLFKTMG TADSQNRMWL LPEETLYLVE RGSMECWSEE GLPMSLQAVY SASIPLCGSL  60
   61 ENYLVYAHLR RCGFSVIRSN LVPVKEDEYR CDSKIMNFKD LLFLGLGKAS QILQTFNFRK 120
  121 LAFPFSKRRR QSILLHDTFY TYEEVYHDLQ IVRGY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.39794
Match:	2cv8A
Description:	Crystal structure of tRNA-intron endonuclease from Sulfolobus tokodaii
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [255-384]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPIACNLITS SDSLFQITFH AYKPSASFKK SALSEPDFRI CVVSSQDTLL PTIFEIDALF  60
   61 SSTPLRQNMP QHMFQRLKEG YRNIIIAIVD YGVISYIRLS DVCFEEKVYT DFSKKGSKRK 120
  121 RVSKKFQQLV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits