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View Structure Prediction Details

Protein: nup120
Organism: Schizosaccharomyces pombe
Length: 1136 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nup120.

Description E-value Query
Range
Subject
Range
gi|38104517, gi|... - gi|39945696|ref|XP_362385.1| hypothetical protein MGG_04831 [Magnaporthe grisea 70-15], gb|EAA51071....
1015.0 [0..34] [1104..35]
gi|28926930, gi|... - gi|32422999|ref|XP_331941.1| hypothetical protein [Neurospora crassa], gi|28926930|gb|EAA35891.1| co...
gi|85116820 - gi|85116820|ref|XP_965127.1| hypothetical protein NCU02742 [Neurospora crassa OR74A]
1014.0 [0..30] [1093..39]
NUP160 - nucleoporin 160kDa
973.0 [0..46] [1099..71]
gi|114637568 - gi|114637568|ref|XP_001170076.1| PREDICTED: nucleoporin 160kDa isoform 1 [Pan troglodytes]
967.0 [0..46] [1099..71]
NU160_MOUSE - Nuclear pore complex protein Nup160 OS=Mus musculus GN=Nup160 PE=1 SV=2
965.0 [0..19] [1099..27]
gi|109468410 - gi|109468410|ref|XP_230286.4| PREDICTED: similar to nucleoporin 160 [Rattus norvegicus]
923.0 [0..44] [1099..34]

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Predicted Domain #1
Region A:
Residues: [1-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNELKHAVVP IDLQSFCLEG TLALWVPALE NDSEDDSEAI ETADDNEKLF KKECVAYDAG  60
   61 VYTSNKSKGS QTLRWSIFQN RTLTIFDVSL NSKKEPLSKF NVKIHFPSNV MKDGVAFSFS 120
  121 EHSDTTIIYA ITHARVLYYI RLSKTWFQLP DARLDDDWCL CYRPISFLNQ KPDLMAAIST 180
  181 SEICVSFFNG GLTKIILNPK DASHYEQHID DSSYLFSLKK YLSLQAFKAD YRSPNTIISM 240
  241 IFLSTYNVLV MLSLDYKLKV LDLSTNQCVE TIELSQTILP LQSFPYLTSD HTTNSFIALY 300
  301 YPDNSHGSFS IYKLNANAHS FKLNVVIEKG IIPPSLPDDE FIPWMLSDFQ LISSEGSQSK 360
  361 FLLIIAWKSN LNTVIQKCNL SLDQDESFSC VWSHSLDSFS LIEKTFFDVP TNMSSGDISE 420
  421 IWLQHIFAHN TSIESIQVAL LSFQNSSSQV SKNKLDKFGA LTISELKNAV LSSIVSTIQI 480
  481 EPNSDLTGYD YYEYKRLLYN EWERFAKLVA YLDHFGDEIL SINFDPSNAV TYINYANKVA 540
  541 FIRDPYLIES FDEEPLTKLI SSLET

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.02
Match: 1pguA
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.23598589443994 bayes_pls_golite062009
RNA binding 1.36802414720047 bayes_pls_golite062009
protein binding 1.35242477415251 bayes_pls_golite062009
transporter activity 1.23232041140488 bayes_pls_golite062009
substrate-specific transporter activity 0.750051725890322 bayes_pls_golite062009
protein transporter activity 0.487974053204324 bayes_pls_golite062009
cytoskeletal protein binding 0.271959658140432 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0245411309982146 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [566-720]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDPSLIEGYQ ILDLGRSLHS CMSFSTLSEI RYSLRELVQD LPSYSLFDTL WVFYDKHIYP  60
   61 NVDPDYISTL IDTLVSLENP MRDIDSLIQR LRSFDIYNHS AQSPSLFLCA SVARVLDSIL 120
  121 KKFQVSIEGF IFLLSLITSQ QDYELQSKFA GCDKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [721-880]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLSLLEDWRL VSFLLENSAL LLEKFEEEDV DSTNCNLNTM EALASVNTAL QFFSALNYSE  60
   61 CFSESQISPL HATVISSLSA IFIRDDTEND LVTELVEKLF LFKQYNACMQ LIGWLNSDPI 120
  121 AVYLKALIYL KSKEAVKAVR CFKTTSLVLY SHTSQFAVLR 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [881-1052]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFQEIAEKYH HQNLLSCYYL HLSKKLFEES AYIDALEFSL LADASKETDD EDLSIAITHE  60
   61 TLKTACAAGK FDAAHVALMV LSTTPLKKSC LLDFVNQLTK QGKINQLLNY SMPTLRQDVD 120
  121 NLLERKAFQM INVESQPCWY NILFSWRYKH QNYRDAAAII YEKLSRYIST TE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1053-1136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LIGKKERTFI IEHYLIVLNT LELLPKEDTW ILVTDMSVDK EPDPNFLPQK LLTLDAIVAE  60
   61 YHLQLKDVAV QVTAEMSSAM NIDL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle