YRC Public Data Repository - Protein Structure Prediction

Protein:	fim1
Organism:	Schizosaccharomyces pombe
Length:	614 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fim1.

Description	E-value	Query Range	Subject Range
gi\|45201164, gi\|... - gi\|45201164\|ref\|NP_986734.1\| AGR069Cp [Ashbya gossypii ATCC 10895], gi\|44985947\|gb\|AAS54558.1\| AGR06... gi\|44985947 - gi\|44985947\|gb\|AAS54558.1\| AGR069Cp [Ashbya gossypii ATCC 10895]	483.0	[0..1]	[614..1]
SAC6 - Fimbrin, actin-bundling protein; cooperates with Scp1p (calponin/transgelin) in the organization and... FIMB_YEAST - Fimbrin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAC6 PE=1 SV=1	478.0	[0..1]	[614..1]
gi\|49524361 - gi\|49524361\|emb\|CAG57958.1\| unnamed protein product [Candida glabrata] gi\|49524361, gi\|... - gi\|50285259\|ref\|XP_445058.1\| unnamed protein product [Candida glabrata], gi\|49524361\|emb\|CAG57958.1\|...	476.0	[0..1]	[614..1]
gi\|71021369, gi\|... - gi\|71021369\|ref\|XP_760915.1\| hypothetical protein UM04768.1 [Ustilago maydis 521], ref\|XP_402383.1\| ...	471.0	[0..1]	[614..1]
gi\|71000794, gi\|... - gi\|71000794\|ref\|XP_755078.1\| actin-bundling protein Sac6 [Aspergillus fumigatus Af293], gi\|66852716\|... gi\|159129177 - gi\|159129177\|gb\|EDP54291.1\| actin-bundling protein Sac6, putative [Aspergillus fumigatus A1163]	465.0	[0..1]	[613..1]
gi\|115385992, gi... - gi\|115385992\|ref\|XP_001209536.1\| fimbrin [Aspergillus terreus NIH2624], gi\|114190535\|gb\|EAU32235.1\| ...	464.0	[0..1]	[612..1]
gi\|50311873, gi\|... - gi\|50311873\|ref\|XP_455968.1\| unnamed protein product [Kluyveromyces lactis], gi\|49645104\|emb\|CAG9867... gi\|49645104 - gi\|49645104\|emb\|CAG98676.1\| KLLA0F19778p [Kluyveromyces lactis]	462.0	[0..1]	[614..1]
gi\|83775252 - gi\|83775252\|dbj\|BAE65375.1\| unnamed protein product [Aspergillus oryzae] gi\|169784092 - gi\|169784092\|ref\|XP_001826508.1\| hypothetical protein [Aspergillus oryzae RIB40]	459.0	[0..1]	[613..1]
gi\|49646889, gi\|... - gi\|50547107\|ref\|XP_501023.1\| hypothetical protein [Yarrowia lipolytica], gi\|49646889\|emb\|CAG83276.1\|...	457.0	[0..1]	[614..1]
gi\|109120673, gi... - gi\|109120677\|ref\|XP_001098697.1\| PREDICTED: L-plastin isoform 5 [Macaca mulatta], gi\|109120675\|ref\|X...	456.0	[0..14]	[612..7]

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Predicted Domain #1

Region A:
Residues: [1-91]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLALKLQKKY PELTNEEILT LTDQFNKLDV DGKGYLDQPT TIKAFEDSKK GSYDEVREAI  60
   61 REVNVDSSGR VEPEDFVGIF NVLKKGVEGT E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.39794
Match:	2f2oA
Description:	Structure of calmodulin bound to a calcineurin peptide: a new way of making an old binding mode
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [92-614]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKKGRITIKG SSSSVSHTIN EEERREFIKH INSVLAGDPD VGSRVPINTE TFEFFDQCKD  60
   61 GLILSKLIND SVPDTIDERV LNKQRNNKPL DNFKCIENNN VVINSAKAMG GISITNIGAG 120
  121 DILEGREHLI LGLVWQIIRR GLLGKIDITL HPELYRLLEE DETLDQFLRL PPEKILLRWF 180
  181 NYHLKAANWP RTVSNFSKDV SDGENYTVLL NQLAPELCSR APLQTTDVLQ RAEQVLQNAE 240
  241 KLDCRKYLTP TAMVAGNPKL NLAFVAHLFN THPGLEPLNE EEKPEIEPFD AEGEREARVF 300
  301 TLWLNSLDVT PSIHDFFNNL RDGLILLQAY DKITPNTVNW KKVNKAPASG DEMMRFKAVE 360
  361 NCNYAVDLGK NQGFSLVGIQ GADITDGSRT LTLALVWQMM RMNITKTLHS LSRGGKTLSD 420
  421 SDMVAWANSM AAKGGKGSQI RSFRDPSIST GVFVLDVLHG IKSEYVDYNL VTDGSTEELA 480
  481 IQNARLAISI ARKLGAVIFI LPEDIVAVRP RLVLHFIGSL MAV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	124.0
Match:	1rt8A
Description:	CRYSTAL STRUCTURE OF THE ACTIN-CROSSLINKING CORE OF SCHIZOSACCHAROMYCES POMBE FIMBRIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
actin binding	7.50245214720686	bayes_pls_golite062009
cytoskeletal protein binding	6.48140000563569	bayes_pls_golite062009
actin filament binding	5.47084878097979	bayes_pls_golite062009
tubulin binding	4.22039137964246	bayes_pls_golite062009
microtubule binding	4.15537672860167	bayes_pls_golite062009
binding	2.8655705697659	bayes_pls_golite062009
structural constituent of cytoskeleton	2.57886434162184	bayes_pls_golite062009
protein binding	2.36488136094907	bayes_pls_golite062009
microtubule plus-end binding	2.0465241878708	bayes_pls_golite062009
structural constituent of muscle	1.32485442580942	bayes_pls_golite062009
structural molecule activity	1.00964022808548	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: