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View Structure Prediction Details

Protein: spp27
Organism: Schizosaccharomyces pombe
Length: 233 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for spp27.

Description E-value Query
Range
Subject
Range
gi|50806703 - gi|50806703|ref|XP_424488.1| PREDICTED: similar to SMARCD1 protein [Gallus gallus]
237.0 [0..34] [233..433]
gi|114644835 - gi|114644835|ref|XP_001155773.1| PREDICTED: SWI/SNF-related matrix-associated actin-dependent regula...
234.0 [0..34] [233..330]
gi|50418293 - gi|50418293|gb|AAH77955.1| Smarcd1 protein [Xenopus laevis]
228.0 [0..34] [233..204]
gi|89267384 - gi|89267384|emb|CAJ82676.1| SWI/SNF related, matrix associated, actin dependent regulator of chromat...
228.0 [0..34] [233..199]
gi|73996696 - gi|73996696|ref|XP_543674.2| PREDICTED: similar to SWI/SNF-related matrix-associated actin-dependent...
228.0 [0..34] [233..276]
gi|109096584 - gi|109096584|ref|XP_001111244.1| PREDICTED: similar to SWI/SNF-related matrix-associated actin-depen...
228.0 [0..34] [233..330]

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Predicted Domain #1
Region A:
Residues: [1-61]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEYETDIKQ ILGTVDRQTV SAKQVRQLLE ERRKVDLSAH KKDLNALILK CFDETAAPSE  60
   61 K

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.14
Match: 1q1vA
Description: Structure of the Oncoprotein DEK: a putative DNA-binding Domain Related to the Winged Helix Motif
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.63842828741542 bayes_pls_golite062009
transcription regulator activity 2.62775554429027 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.953438255689584 bayes_pls_golite062009
histone binding 0.948950535074526 bayes_pls_golite062009
protein binding 0.529408559970229 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.439630834571696 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [62-233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESLEKQAPAR KTKGKRATEN GTEEGKKPAK RTRKRKEDGE EGGKRKRNQD PANNPLNKPM  60
   61 KLSPKLAEFL GLEQLSRPQT VKKLWEYIKA HDLQDPNDKR TILCDDKLKS VFEVDTLHMF 120
  121 TMNKYLTNLM TKIPDDQLPK PQPKNEEPAA PNDLPKQEEK ELVEPPTAES TA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.69897
Match: 1uhrA
Description: Solution structure of the SWIB domain of mouse BRG1-associated factor 60a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.01592136607858 bayes_pls_golite062009
binding 3.20303599400601 bayes_pls_golite062009
basal transcription repressor activity 2.69162769894095 bayes_pls_golite062009
transcription coactivator activity 2.58234407051051 bayes_pls_golite062009
transcription repressor activity 1.98538788872171 bayes_pls_golite062009
transcription activator activity 1.83085389017135 bayes_pls_golite062009
transcription factor binding 1.73032563380905 bayes_pls_golite062009
transcription cofactor activity 1.60414428986898 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.51390743508971 bayes_pls_golite062009
protein binding 1.38134467541454 bayes_pls_golite062009
ligase activity 0.802664465339603 bayes_pls_golite062009
structural molecule activity 0.66106995897056 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.15313128037113 bayes_pls_golite062009
catalytic activity 0.121624777548864 bayes_pls_golite062009

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