YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC11E10.07c
Organism:	Schizosaccharomyces pombe
Length:	341 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC11E10.07c.

Description	E-value	Query Range	Subject Range
MTNA_THEMA - Methylthioribose-1-phosphate isomerase OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 /... MTNA_THEMA - Methylthioribose-1-phosphate isomerase OS=Thermotoga maritima GN=mtnA PE=1 SV=1	335.0	[0..8]	[339..27]
gi\|91200837 - gi\|91200837\|emb\|CAJ73891.1\| conserved hypothetical protein [Candidatus Kuenenia stuttgartiensis]	330.0	[0..9]	[338..24]
R15PI_THEKO - Ribose 1,5-bisphosphate isomerase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KO...	328.0	[0..13]	[340..4]
MTNA_NOSP7 - Methylthioribose-1-phosphate isomerase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=mtnA...	328.0	[0..9]	[339..31]
R15PI_PYRAB - Ribose 1,5-bisphosphate isomerase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=PYRAB01930 PE=3 SV=1 E2B2_PYRAB, EI2B... - Putative translation initiation factor eIF-2B subunit 2 OS=Pyrococcus abyssi GN=aIF-2BII PE=3 SV=1, ...	328.0	[0..13]	[340..6]
MTNA_CLOTH - Methylthioribose-1-phosphate isomerase OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / N... gi\|196253138, gi... - gi\|196253138\|ref\|ZP_03151778.1\| translation initiation factor, aIF-2BI family [Clostridium thermocel...	328.0	[0..7]	[340..22]
gi\|52144901, gi\|... - gi\|52144901\|ref\|YP_081928.1\| translation initiation factor IF-2B subunit alpha [Bacillus cereus E33L...	326.0	[0..12]	[340..35]
MTNA_GEOSL - Methylthioribose-1-phosphate isomerase OS=Geobacter sulfurreducens GN=mtnA PE=3 SV=1 MTNA_GEOSL - Methylthioribose-1-phosphate isomerase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / ...	326.0	[0..12]	[327..29]
gi\|228925590, gi... - gi\|228925590\|ref\|ZP_04088679.1\| Translation initiation factor, aIF-2BI [Bacillus thuringiensis serov... gi\|227813012, gi... - gi\|227813012\|ref\|YP_002813021.1\| S-methyl-5-thioribose-1-phosphate isomerase [Bacillus anthracis str... gi\|228944142, gi... - gi\|228944142\|ref\|ZP_04106521.1\| Translation initiation factor, aIF-2BI [Bacillus thuringiensis serov... gi\|228827816, gi... - gi\|228931836\|ref\|ZP_04094732.1\| Translation initiation factor, aIF-2BI [Bacillus thuringiensis serov... gi\|229600223, gi... - gi\|229600223\|ref\|YP_002864962.1\| S-methyl-5-thioribose-1-phosphate isomerase [Bacillus anthracis str... gi\|118476095, gi... - gi\|118476095\|ref\|YP_893246.1\| methylthioribose-1-phosphate isomerase [Bacillus thuringiensis str. Al... gi\|228663459, gi... - gi\|229119993\|ref\|ZP_04249248.1\| Translation initiation factor, aIF-2BI [Bacillus cereus 95/8201], gi... gi\|49183360, gi\|... - gi\|49183360\|ref\|YP_026612.1\| translation initiation factor IF-2B subunit alpha [Bacillus anthracis s... gi\|65317770 - gi\|65317770\|ref\|ZP_00390729.1\| COG0182: Predicted translation initiation factor 2B subunit, eIF-2B a... gi\|170126170, gi... - gi\|170708937\|ref\|ZP_02899370.1\| putative translation initiation factor, aIF-2BI family [Bacillus ant... gi\|177653696, gi... - gi\|177653696\|ref\|ZP_02935835.1\| putative translation initiation factor, aIF-2BI family [Bacillus ant... gi\|165871411, gi... - gi\|165871411\|ref\|ZP_02216059.1\| putative translation initiation factor, aIF-2BI family [Bacillus ant... gi\|167511915, gi... - gi\|167640104\|ref\|ZP_02398371.1\| putative translation initiation factor, aIF-2BI family [Bacillus ant... gi\|196028960, gi... - gi\|196040105\|ref\|ZP_03107407.1\| putative translation initiation factor, aIF-2BI family [Bacillus cer... gi\|218901537, gi... - gi\|218901537\|ref\|YP_002449371.1\| putative translation initiation factor, aIF-2BI family [Bacillus ce... gi\|190561360, gi... - gi\|190567573\|ref\|ZP_03020486.1\| putative translation initiation factor, aIF-2BI family [Bacillus ant... gi\|225789584, gi... - gi\|225862384\|ref\|YP_002747762.1\| S-methyl-5-thioribose-1-phosphate isomerase [Bacillus cereus 03BB10... gi\|195992689, gi... - gi\|196034646\|ref\|ZP_03102054.1\| putative translation initiation factor, aIF-2BI family [Bacillus cer...	325.0	[0..12]	[340..35]
MTNA1_BACAN - Methylthioribose-1-phosphate isomerase 1 OS=Bacillus anthracis GN=mtnA1 PE=3 SV=1 MTNA1_BACAH - Methylthioribose-1-phosphate isomerase 1 OS=Bacillus thuringiensis (strain Al Hakam) GN=mtnA1 PE=3 S... gi\|254724807 - gi\|254724807\|ref\|ZP_05186590.1\| methylthioribose-1-phosphate isomerase [Bacillus anthracis str. A105... gi\|254761928 - gi\|254761928\|ref\|ZP_05213777.1\| methylthioribose-1-phosphate isomerase [Bacillus anthracis str. Aust... gi\|47500762, gi\|... - gi\|47525614\|ref\|YP_016963.1\| translation initiation factor IF-2B subunit alpha [Bacillus anthracis s... gi\|30260517, gi\|... - gi\|30260517\|ref\|NP_842894.1\| translation initiation factor IF-2B subunit alpha [Bacillus anthracis s... gi\|254739045 - gi\|254739045\|ref\|ZP_05196747.1\| methylthioribose-1-phosphate isomerase [Bacillus anthracis str. West... gi\|21398293 - ref\|NP_654278.1\| IF-2B, Initiation factor 2 subunit family [Bacillus anthracis str. A2012] gi\|254756110 - gi\|254756110\|ref\|ZP_05208139.1\| methylthioribose-1-phosphate isomerase [Bacillus anthracis str. Voll...	325.0	[0..12]	[340..34]

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Predicted Domain #1

Region A:
Residues: [1-341]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVESDSSGIV RHSQGEFDIV QVYKKFLQDD PEITMPVAAI EALVQLLSRS QAKTISEFMD  60
   61 ILQNGSNTLK EGVQNNISLS AGCDIFQRFV TRSLHDVGDF EQCKRHLVEN GKLFIQRARA 120
  121 CRQRIAHLGY PLIRDGSVIL THGFSRGVAA VLLAAAKRHV RFKVFVTESR PSGSGCLMTR 180
  181 TLKNACIPTC MVLDSAVSFT MNRVDLVLVG AEGVVENGGL INQIGTFQLA VFAKHAHKPF 240
  241 YAVAESHKFV RMFPLSQYDI PFSRPILEFD DPSPETVHPE PEPIPTPSDA IHNELIMNEE 300
  301 QIRNNPTLDV TPPEFVSGLI TDLGIIDSKS GVSEELIKLY L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	92.522879
Match:	1t9kA
Description:	X-ray crystal structure of aIF-2B alpha subunit-related translation initiation factor [Thermotoga maritima]
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation initiation factor activity	10.1099993541596	bayes_pls_golite062009
translation regulator activity	5.74669335554405	bayes_pls_golite062009
nucleic acid binding	2.17718456512191	bayes_pls_golite062009
transcription regulator activity	1.9283980201455	bayes_pls_golite062009
DNA binding	1.55389679363348	bayes_pls_golite062009
binding	1.53908996868286	bayes_pls_golite062009
catalytic activity	1.31732715713197	bayes_pls_golite062009
translation factor activity, nucleic acid binding	1.09424756417577	bayes_pls_golite062009
transcription repressor activity	1.03828732072006	bayes_pls_golite062009
transcription factor activity	0.995059566132783	bayes_pls_golite062009
sugar binding	0.319281682893106	bayes_pls_golite062009
protein binding	0.0293610121675921	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: