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View Structure Prediction Details

Protein: SPCC1259.02c
Organism: Schizosaccharomyces pombe
Length: 822 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC1259.02c.

Description E-value Query
Range
Subject
Range
CG30043-PA - This gene is referred to in FlyBase by the symbol Dmel\CG30043 (CG30043, FBgn0050043). It is a prote...
607.0 [0..6] [806..29]
gi|55749804 - ref|NP_079172.2| KIAA1815 [Homo sapiens]
ERMP1 - endoplasmic reticulum metallopeptidase 1
594.0 [0..8] [807..66]
gi|54636020, gi|... - gi|54636020|gb|EAL25423.1| GA15600-PA [Drosophila pseudoobscura], gi|125808720|ref|XP_001360848.1| G...
593.0 [0..7] [806..25]
gi|37360558 - gi|37360558|dbj|BAC98257.1| mKIAA1815 protein [Mus musculus]
590.0 [0..43] [807..86]

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Predicted Domain #1
Region A:
Residues: [1-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLVCASSSK CKRNTFLQLA MVLFAVVMAR IALYFHNHLD EPLVDPYDAN GNPQFSEANA  60
   61 LKHVIHLSDD IGYRILGTIE QERAREYIMN EVLALQKQLQ DGPNADIHQM EVSLESGDGA 120
  121 HRFDFMNKYV IKKYQNLKNI VVRLSNGTEA CKEEAVLINA HVDSTLPSPG ATDDALAVAI 180
  181 LLEAIRIFIS RPVPLTHSIV FLFNDAEESL QDASHMFITQ SPLRDTIKCV VNLEACGTTG 240
  241 SEILFQATSN EMIKAYSHVP HPFGTVLADD VFRTGLILSD TDFRQFVQYG NLTGLDMAVV 300
  301 KNSYLYHTKK DLAPYISPGT PQNFGENILA ILTYLVSPEA DLNNMKSSG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.221849
Match: 2ootA
Description: No description for 2ootA was found.

Predicted functions:

Term Confidence Notes
hydrolase activity 1.7824202462173 bayes_pls_golite062009
catalytic activity 1.76936806579991 bayes_pls_golite062009
peptidase activity 1.69812537802871 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.41029347724469 bayes_pls_golite062009
exopeptidase activity 0.82896398764377 bayes_pls_golite062009
carboxypeptidase activity 0.215630276604929 bayes_pls_golite062009
metallopeptidase activity 0.1586028474273 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [350-539]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVYFSVFNSL FFMYSKLTSK ILNTLVGGLG ILLTLRGSEG SFTVALIAQV ISIAGIFVIP  60
   61 NIWAYILGNV LDCGMSWFRN EYWPLFIYLP AIFASLFFTE SLFKRSEHLA LRATIFIFSL 120
  121 LTFIPLPSAY LFTIIDFFMV FALFLNDKIL AKPGTVHPLT YFIGSIGAMT VGFESAINLL 180
  181 EIFVPLTGRI 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [540-660]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTDKVADNVV ATVCVCGFNI YFPLMSPWIQ RFRSRCCFRL GLLFSIFVVG FSSFILAKQD  60
   61 TYYDSLHPRR IFVQRMENIT SNEVSLHIAS ADSAPGFDKL SSDLSSLLTD EPVVKTEMDD 120
  121 W

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [661-822]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSDWDTVYPF SQFLGSYRIP LNDTVDVTTL PSIKFSNKVV KDNVVNVTVT VEHPGLIWTV  60
   61 VSFDADVLSW SLPEVPSTVR RHHVREVSAY GLDSYSFNMS YLEAPIYFDF VGVDGVGHYP 120
  121 SKASEGRDRA SIQLCEKLTN DYLPDWTDTL CIGVVSGNFK LE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.508 0.911 peptidase activity d.92.1 Metalloproteases ("zincins"), catalytic domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle