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View Structure Prediction Details

Protein: SPBP8B7.15c
Organism: Schizosaccharomyces pombe
Length: 482 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBP8B7.15c.

Description E-value Query
Range
Subject
Range
RBBP6_MOUSE - E3 ubiquitin-protein ligase RBBP6 OS=Mus musculus GN=Rbbp6 PE=1 SV=5
256.0 [0..3] [478..2]
gi|149067993, gi... - gi|62641247|ref|XP_219296.3| PREDICTED: similar to retinoblastoma binding protein 6 isoform 1 isofor...
255.0 [0..3] [478..2]
gi|109127941 - gi|109127941|ref|XP_001097618.1| PREDICTED: similar to retinoblastoma-binding protein 6 isoform 2 is...
254.0 [0..3] [478..2]
RBBP6 - retinoblastoma binding protein 6
gi|225000778 - gi|225000778|gb|AAI72357.1| Retinoblastoma binding protein 6 [synthetic construct]
252.0 [0..3] [478..2]
gi|114661628 - gi|114661628|ref|XP_001164014.1| PREDICTED: retinoblastoma-binding protein 6 isoform 6 [Pan troglody...
252.0 [0..3] [478..2]

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Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGVIYYKFK SQKDPSRITF DGTIGMSVFD VKREIIMQKK LGNGLDFDLL LYNANSNEEY  60
   61 DDDTFIIPRS TSVIVRRVPA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.39794
Match: 2c7hA
Description: Solution NMR structure of the DWNN domain from human RBBP6
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [81-164]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKSGKGTAAR YVSGAPKTTG ARSDSVKRPV PMLQKKAPIT SGESNINKSP SSSEDAAIQQ  60
   61 MFQVSSDQWR ETQDKMASAT PIYK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.522879
Match: 1bajA
Description: HIV-1 CAPSID PROTEIN C-TERMINAL FRAGMENT PLUS GAG P2 DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.04588712677166 bayes_pls_golite062009
DNA binding 2.53317408686316 bayes_pls_golite062009
nucleic acid binding 2.33828046499668 bayes_pls_golite062009
binding 2.07015157850093 bayes_pls_golite062009
transcription factor activity 2.0090791129794 bayes_pls_golite062009
transcription activator activity 0.68790059848359 bayes_pls_golite062009
protein binding 0.214213089360409 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [165-333]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNQRRIAASV PDKPPPPGYI CYRCGQKGHW IQACPTNADP NYDGKPRVKR TTGIPRSFLK  60
   61 NVERPAEGDA ANIMINAEGD YVVVQPDVAS WETYQSRKAA LTANDVYKMQ PPNISLACTL 120
  121 CKKLARNACR TPCCDKLFCE ECIQTALLDS DFECPNCHRK DVLLDTLNP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.0
Match: 1fbvA
Description: Cbl; N-terminal domain of cbl (N-cbl); CBL
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.53440610777794 bayes_pls_golite062009
protein binding 1.44943024889856 bayes_pls_golite062009
transcription regulator activity 1.21787427710133 bayes_pls_golite062009
nucleic acid binding 0.989403795332031 bayes_pls_golite062009
DNA binding 0.919230170522211 bayes_pls_golite062009
transcription factor activity 0.381732656457041 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [334-398]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYQKQREIEA VVKSVLGSNS KNSDKVGTSD DNNTPMSEKR KREDDDANGP NKFAARSSAV  60
   61 FSKAT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.39794
Match: 2cklB
Description: No description for 2cklB was found.

Predicted Domain #5
Region A:
Residues: [399-482]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEPAFKSAMA IPDMPSMPHV QGFPAPFPPF MMPGLPQMPP MMMNAIAGQV YHNNRNPPRT  60
   61 NSRPSNASVP PPSSLHKNPP TKTN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle