YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC757.04
Organism:	Schizosaccharomyces pombe
Length:	684 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC757.04.

Description	E-value	Query Range	Subject Range
YCV2_SCHPO - Uncharacterized transcriptional regulatory protein C777.02 OS=Schizosaccharomyces pombe (strain 972 ... SPCC777.02 - transcription factor	272.0	[0..56]	[668..26]
gi\|50549381, gi\|... - gi\|50549381\|ref\|XP_502161.1\| YALI0C22990p [Yarrowia lipolytica], gi\|49648028\|emb\|CAG82481.1\| unnamed... gi\|49648028 - gi\|49648028\|emb\|CAG82481.1\| YALI0C22990p [Yarrowia lipolytica]	254.0	[0..38]	[607..17]
gi\|114187620, gi... - gi\|115449691\|ref\|XP_001218671.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	233.0	[0..26]	[670..222]
gi\|245224 - gi\|245224\|gb\|AAB21394.1\| NIT4=protein product involved in nitrate assimilation [Neurospora intermedi... NIT4_NEUCR - Nitrogen assimilation transcription factor nit-4 - Neurospora crassa	230.0	[0..14]	[684..10]
NIT4_NEUCR - Nitrogen assimilation transcription factor nit-4 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1... NIT4_NEUCR - Nitrogen assimilation transcription factor nit-4 OS=Neurospora crassa GN=nit-4 PE=4 SV=2	230.0	[0..14]	[684..10]
gi\|50409605, gi\|... - gi\|50409605\|ref\|XP_456889.1\| hypothetical protein DEHA0A13321g [Debaryomyces hansenii CBS767], gi\|49...	230.0	[0..47]	[659..35]
gi\|6901427 - gi\|6901427\|emb\|CAB71797.1\| pathway-specific nitrogen regulator [Tolypocladium inflatum]	227.0	[0..1]	[662..15]
gi\|67537316, gi\|... - gi\|67537316\|ref\|XP_662432.1\| hypothetical protein AN4828.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	223.0	[0..17]	[675..357]

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Predicted Domain #1

Region A:
Residues: [1-175]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHMDSERLL FKRYLQRLFI TRILTLIRLD LSLFRRYNTN TIVGSVAYET LVDTVCDVSS  60
   61 NSTFVVKCNR QYPCTRCLKY GEACTYDERD NRKKRHSLSY LHSLESQLAR LESFIMTLKN 120
  121 SDPEGRDEML KSVVFSDHLT EPNDQEVKSE GPIEYPVFLN VQDSKTVSFY GPTSA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.32
Match:	1pyiA
Description:	PPR1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.34861813464065	bayes_pls_golite062009
DNA binding	4.03985756894684	bayes_pls_golite062009
nucleic acid binding	3.97978190843512	bayes_pls_golite062009
transcription factor activity	2.87348461329489	bayes_pls_golite062009
binding	2.82809978070212	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.80191339934741	bayes_pls_golite062009
sequence-specific DNA binding	1.67344049333457	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	1.50774349911815	bayes_pls_golite062009
transcription activator activity	0.822069987038721	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [176-256]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDLSLPDITK DNKTTWNFQA SYSPMVSECL KLFFRYQYSQ FLFVYRESFL SDYYYNFHDG  60
   61 FYCTEHLIYA ICAIGASMSD D

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.480	0.866	cytosol	a.1.1	Globin-like
View	Download	0.479	0.866	cytosol	a.118.9	ENTH/VHS domain
View	Download	0.682	0.866	cytosol	a.29.2	Bromodomain
View	Download	0.517	0.866	cytosol	a.29.2	Bromodomain
View	Download	0.468	0.866	cytosol	a.29.2	Bromodomain

Predicted Domain #3

Region A:
Residues: [257-380]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENISRHSKSY YDASWQKLLE FGLDRSHLTS VQCLLCLGYY DIGMGNTSLG WLLSGLAFRM  60
   61 GQDLGFQLNP ENWYIDNSPA ISSADSDIRR RVFWGSYVAD KFIGFIMGRP TMLKRSDASI 120
  121 PGSN

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	31.823909
Match:	PF04082.9
Description:	No description for PF04082.9 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.591	0.004	cytosol	a.100.1	6-phosphogluconate dehydrogenase C-terminal domain-like
View	Download	0.697	0.002	cytosol	a.7.8	GAT domain
View	Download	0.729	0.001	cytosol	a.24.16	Nucleotidyltransferase substrate binding subunit/domain
View	Download	0.751	N/A	N/A	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain
View	Download	0.711	N/A	N/A	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain

Predicted Domain #4

Region A:
Residues: [381-465]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLPEFAGLEE FKLNVTDYMS LTDFSVCDAV ALFVDLSDIA DSILLNMFSP TSKNRATNIN  60
   61 CVLSNLGKYN LELMNWHYKL PDTIS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [466-684]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WRTIDLKKDR IPNLCAVSLY YHLIRICLNR PFLSRKEVTA NDLTPKTICT DSINEIVTVI  60
   61 RAHRTANGLR YSTLYIVYAA IVSCSVILLL RDMCTDSELL TLNNDMMFFI EVLKECSQTW 120
  121 KLAQRSIVLI ENTLKGKTNS QSTSEFVSPI SDTENGSSSQ QVSEAKDIVE PSDVLDELQK 180
  181 FDLLPENDDN FQTFQAFYGG PPIILSPNLY EKKLNEKTL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: