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View Structure Prediction Details

Protein: fap2
Organism: Schizosaccharomyces pombe
Length: 433 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fap2.

Description E-value Query
Range
Subject
Range
CG6385-PA - This gene is referred to in FlyBase by the symbol Dmel\CG6385 (CG6385, FBgn0034276). It is a protein...
232.0 [0..3] [433..37]
gi|108868599, gi... - gi|157107996|ref|XP_001650030.1| sarcosine dehydrogenase [Aedes aegypti], gi|108868599|gb|EAT32824.1...
231.0 [0..2] [433..44]
gi|227338884, gi... - gi|36958750|gb|AAQ87218.1| Dimethylglycine dehydrogenase [Rhizobium sp. NGR234], gi|227819885|ref|YP...
230.0 [0..3] [433..8]
gi|54636954, gi|... - gi|54636954|gb|EAL26357.1| GA19555-PA [Drosophila pseudoobscura], gi|125811176|ref|XP_001361778.1| G...
228.0 [0..2] [433..40]
gi|15075297 - gi|15075297|emb|CAC46853.1| Probable sarcosine dehydrogenase [Sinorhizobium meliloti 1021]
gi|15966027 - gi|15966027|ref|NP_386380.1| putative oxidoreductase protein [Sinorhizobium meliloti 1021]
227.0 [0..3] [433..9]
SARDH_RAT - Sarcosine dehydrogenase, mitochondrial OS=Rattus norvegicus GN=Sardh PE=1 SV=2
224.0 [0..2] [433..67]
gi|13471340, gi|... - gi|14022085|dbj|BAB48695.1| sarcosine dehydrogenase [Mesorhizobium loti MAFF303099], gi|13471340|ref...
224.0 [0..3] [433..9]
gi|115254511, gi... - gi|116249863|ref|YP_765701.1| pyruvate dehydrogenase phosphatase regulatory subunit [Rhizobium legum...
223.0 [0..2] [433..8]

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Predicted Domain #1
Region A:
Residues: [1-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRTIVIVGC GVFGLSTAVE LAKNHSFDNI IAIDAEPVPS SMSAANDINK IVRPEYADLK  60
   61 YMKLALEAME KWRNDPELSS VYFECGRLST ISKDPYRARF DEVAQRNLRK LLGDSALINL 120
  121 SSSEEIRKKY PSLFSNSPLR SDMQAVVNEH AGYANSAASL KLLELKAREL GVEFVFGKAG 180
  181 KFKKFVVNHS ETDIDKNDNH VSVQTEDGTI YHADTILLAV GAYLNAYLNT SHRVCAKGLP 240
  241 VAHIQLTDEE FKTYKNMPII FDPDCAYAFP PYPVTKLIKL ASTGYEYVCN VETDYDENSK 300
  301 VVSIPHSGPS KSSLPKYAII QMRRFLDTFL PDLADRSLIN TKMCWISDTE DANFLIDKVP 360
  361 QFDNVFVANG DSGHAFKFLP NIGRYIAQRI LGDLSEEWKD AWRWREDDKA SELKWRCVRS 420
  421 LIDYKDAEFT YDK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.69897
Match: 1el5A
Description: Sarcosine oxidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 1.61125987248836 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.07245967881566 bayes_pls_golite062009
catalytic activity 1.03127962968326 bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity 0.681230241795345 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors 0.397770205910041 bayes_pls_golite062009
oxidoreductase activity 0.18223312042771 bayes_pls_golite062009

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