YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC2E1P5.03
Organism:	Schizosaccharomyces pombe
Length:	303 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC2E1P5.03.

Description	E-value	Query Range	Subject Range
gi\|82703356, gi\|... - gi\|82703356\|ref\|YP_412922.1\| heat shock protein DnaJ [Nitrosospira multiformis ATCC 25196], gi\|82411...	194.0	[0..32]	[221..6]
gi\|112180618, gi... - gi\|70794764\|ref\|NP_001020582.1\| DnaJ (Hsp40) homolog, subfamily A, member 4 [Rattus norvegicus], gi\|...	191.0	[0..14]	[220..138]
gi\|32450159, gi\|... - gi\|32450159\|gb\|AAH53791.1\| Dnaja2-prov protein [Xenopus laevis], gi\|148227640\|ref\|NP_001080625.1\| Dn...	189.0	[0..38]	[218..6]
gi\|124530383, gi... - gi\|124530383\|ref\|ZP_01701069.1\| chaperone protein DnaJ [Escherichia coli B], gi\|124499274\|gb\|EAY4676... gi\|110640228, gi... - gi\|110640228\|ref\|YP_667956.1\| chaperone protein DnaJ [Escherichia coli 536], gi\|110341820\|gb\|ABG6805...	188.0	[0..34]	[220..9]
gi\|117622308, gi... - gi\|117622308\|ref\|YP_851221.1\| chaperone protein DnaJ [Escherichia coli APEC O1], gi\|115511432\|gb\|ABI... gi\|226902067, gi... - gi\|237704155\|ref\|ZP_04534636.1\| chaperone with DnaK [Escherichia sp. 3_2_53FAA], gi\|226902067\|gb\|EEH...	188.0	[0..32]	[220..7]
DNAJ_SHIDS - Chaperone protein DnaJ OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=dnaJ PE=3 SV=1	187.0	[0..36]	[220..1]
gi\|119619583, gi... - gi\|50950039\|emb\|CAH10558.1\| hypothetical protein [Homo sapiens], gi\|194328758\|ref\|NP_061072.3\| DnaJ ...	187.0	[0..32]	[220..27]
DNAJ_SHIBS - Chaperone protein DnaJ OS=Shigella boydii serotype 4 (strain Sb227) GN=dnaJ PE=3 SV=1 DNAJ_SHIB3 - Chaperone protein DnaJ OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=dnaJ PE=3 SV=1	187.0	[0..36]	[220..1]
gi\|30351104, gi\|... - gi\|47523738\|ref\|NP_999504.1\| DnaJ (Hsp40) homolog, subfamily A, member 4 [Sus scrofa], gi\|30351104\|g...	187.0	[0..35]	[220..1]
gi\|188495716, gi... - gi\|75515606\|ref\|ZP_00737763.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|168785065, gi... - gi\|189374927\|gb\|EDU93343.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC869], gi\|1687850... sp\|B7UI60\|DNAJ_ECO27 - Chaperone protein dnaJ OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=dnaJ PE=3 SV=1 DNAJ_SHISS - Chaperone protein DnaJ OS=Shigella sonnei (strain Ss046) GN=dnaJ PE=3 SV=1 gi\|168762775, gi... - gi\|189366928\|gb\|EDU85344.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC4501], gi\|168762... gi\|192956076, gi... - gi\|75234578\|ref\|ZP_00718919.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... DNAJ_ECOSM - Chaperone protein DnaJ OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=dnaJ PE=3 SV=1 gi\|193065637, gi... - gi\|75256327\|ref\|ZP_00727999.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|189379547, gi... - gi\|189379547\|gb\|EDU97963.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC508], gi\|1687979... DNAJ_ECO27 - Chaperone protein DnaJ OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=dnaJ PE=3 SV=1 DNAJ_ECOSE - Chaperone protein DnaJ OS=Escherichia coli (strain SE11) GN=dnaJ PE=3 SV=1 DNAJ_ECOL6 - Chaperone protein DnaJ OS=Escherichia coli O6 GN=dnaJ PE=2 SV=3 DNAJ_ESCF3 - Chaperone protein DnaJ OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) GN=dn... gi\|217325343, gi... - gi\|217325343\|ref\|ZP_03441427.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. TW14588], gi\|2... DNAJ_ECOUT - Chaperone protein DnaJ OS=Escherichia coli (strain UTI89 / UPEC) GN=dnaJ PE=3 SV=1 gi\|15829269, gi\|... - gi\|15829269\|ref\|NP_308042.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. Sakai], gi\|133594... gi\|75229476, gi\|... - gi\|75229476\|ref\|ZP_00716026.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|75235742, gi\|... - gi\|75235742\|ref\|ZP_00719906.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... DNAJ_ECO24 - Chaperone protein DnaJ OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=dnaJ PE=3 SV=1 DNAJ_ECOHS - Chaperone protein DnaJ OS=Escherichia coli O9:H4 (strain HS) GN=dnaJ PE=3 SV=1 gi\|209747186, gi... - pir\|\|G85481 chaperone with DnaK, heat shock protein [imported] - Escherichia coli (strain O157:H7, s... DNAJ_ECO57 - Chaperone protein DnaJ OS=Escherichia coli O157:H7 GN=dnaJ PE=3 SV=3 DNAJ_ECOL6 - Chaperone protein DnaJ OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=dnaJ PE=3 S... DNAJ_ECO45 - Chaperone protein DnaJ OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=dnaJ PE=3 SV=1 gi\|12512693, gi\|... - gi\|15799695\|ref\|NP_285707.1\| chaperone protein DnaJ [Escherichia coli O157:H7 EDL933], gi\|12512693\|g... DNAJ_ECO8A - Chaperone protein DnaJ OS=Escherichia coli O8 (strain IAI1) GN=dnaJ PE=3 SV=1 DNAJ_ECO55 - Chaperone protein DnaJ OS=Escherichia coli (strain 55989 / EAEC) GN=dnaJ PE=3 SV=1 DNAJ_ECO81 - Chaperone protein DnaJ OS=Escherichia coli O81 (strain ED1a) GN=dnaJ PE=3 SV=1 DNAJ_ECOLU - Chaperone protein DnaJ OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=dnaJ PE=3 SV=1 DNAJ_ECO7I - Chaperone protein DnaJ OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=dnaJ PE=3 SV=1 gi\|227837919, gi... - gi\|227885090\|ref\|ZP_04002895.1\| chaperone protein DnaJ [Escherichia coli 83972], gi\|227837919\|gb\|EEJ... gi\|229560216 - gi\|229560216\|ref\|YP_667956.2\| chaperone protein DnaJ [Escherichia coli 536] gi\|229775981 - gi\|229775981\|ref\|YP_851221.2\| chaperone protein DnaJ [Escherichia coli APEC O1] DNAJ_ECOLC - Chaperone protein DnaJ OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=dnaJ PE=3 SV=1	187.0	[0..36]	[220..1]

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Predicted Domain #1

Region A:
Residues: [1-137]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRIFILLLL FGVCLAWTSS DLEIFRVVDS LKSILKNKAT FYELLEVPTK ASIKEINRAY  60
   61 RKKSILYHPD KNPKSKELYT LLGLIVNILR NTETRKRYDY FLKNGFPRWK GTGYLYSRYR 120
  121 PGLGAVLVLL FLLISIA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.09691
Match:	1xblA
Description:	NMR STRUCTURE OF THE J-DOMAIN (RESIDUES 2-76) IN THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 2-108) OF THE MOLECULAR CHAPERONE DNAJ, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
unfolded protein binding	3.04403163860617	bayes_pls_golite062009
heat shock protein binding	2.17994194200939	bayes_pls_golite062009
chaperone binding	1.61155546076854	bayes_pls_golite062009
binding	1.60921541945619	bayes_pls_golite062009
protein binding	0.912937133925792	bayes_pls_golite062009
Hsp70 protein binding	0.541755903922701	bayes_pls_golite062009
catalytic activity	0.106988907594358	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [138-226]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HFVMLVISSK RQKKIMQDHI DIARQHESYA TSARGSKRIV QVPGGRRIYT VDSITGQVCI  60
   61 LDPSSNIEYL VSPDSVASVK ISDTFFYRL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.154902
Match:	1nltA
Description:	The crystal structure of Hsp40 Ydj1
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [227-303]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRFIVWNAFG RWFARAPASS EDTDSDGQME DEEKSDSVHK SSFSSPSKKE ASIKAGKRRM  60
   61 KRRANRIPLS KNTNREN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.228	0.004	endoplasmic reticulum	a.144.1	PABC (PABP) domain
View	Download	0.235	0.001	endoplasmic reticulum	a.48.3	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View	Download	0.245	N/A	N/A	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain
View	Download	0.239	N/A	N/A	c.23.12	Formate/glycerate dehydrogenase catalytic domain-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: