YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC3H7.11
Organism:	Schizosaccharomyces pombe
Length:	248 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC3H7.11.

Description	E-value	Query Range	Subject Range
gi\|72040154, gi\|... - gi\|72040154\|ref\|XP_801901.1\| PREDICTED: similar to CG13929-PA, isoform A isoform 4 [Strongylocentrot...	177.0	[0..2]	[247..120]
gi\|54641515, gi\|... - gi\|54641515\|gb\|EAL30265.1\| GA12634-PA [Drosophila pseudoobscura], gi\|125977464\|ref\|XP_001352765.1\| G...	177.0	[0..2]	[247..53]
metl-PB - The gene methyltransferase-like is referred to in FlyBase by the symbol Dmel\metl (CG13929, FBgn0035... gi\|220955912, gi... - gi\|220955912\|gb\|ACL90499.1\| metl-PB [synthetic construct], gi\|220946126\|gb\|ACL85606.1\| metl-PB [synt...	177.0	[0..2]	[247..75]
gi\|20197178, gi\|... - gi\|42570317\|ref\|NP_850075.2\| unknown protein [Arabidopsis thaliana], gi\|20197178\|gb\|AAC14529.2\| hypo...	168.0	[0..7]	[247..28]
gi\|112419026 - gi\|112419026\|gb\|AAI22481.1\| LOC733347 protein [Xenopus laevis]	168.0	[0..7]	[247..89]
gi\|149746384, gi... - gi\|153840045\|ref\|ZP_01992712.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Vibrio p... UBIE_VIBPA - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio parahaemolyticus serotype O3:... UBIE_VIBPA - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio parahaemolyticus GN=ubiE PE=3 S...	168.0	[0..5]	[235..22]
gi\|114771551, gi... - gi\|114771551\|ref\|ZP_01448961.1\| ubiquinone/menaquinone biosynthesis methyltransferase [alpha proteob... gi\|114771551 - gi\|114771551\|ref\|ZP_01448961.1\| ubiquinone/menaquinone biosynthesis methyltransferase [alpha proteob... gi\|221133941 - gi\|221133941\|ref\|ZP_03560246.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Glaciecola sp...	168.0	[0..5]	[235..25]

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Predicted Domain #1

Region A:
Residues: [1-248]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGISKLSDF WVEKYKKESK KSWDKFYKRN ETRFFKDRHW LDREFDCYFG LPDKLPLTIL  60
   61 EVGCGVGNLV YPLLEVQPNL KIYCCDFSPR AIDFVKKHSC YNENRVFPFV NDITEDSLLE 120
  121 VLGSACIDTL TAIFVLSAIP REKQLRSIKN LASVIKPGGH LVFRDYCDGD FAQEKFMTSG 180
  181 DPSMIDEQTF VRQDGTLSLF FREEDIAEWM KSAGFGLVTL DRVNRTVDNR KRNLNMKRTF 240
  241 LQGVWKKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.221849
Match:	2fk7A
Description:	Crystal structure of Hma (MmaA4) from Mycobacterium tuberculosis, apo-form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity	1.55708326065545	bayes_pls_golite062009
protein methyltransferase activity	0.90417202530863	bayes_pls_golite062009
N-methyltransferase activity	0.89763572661057	bayes_pls_golite062009
binding	0.828198443853075	bayes_pls_golite062009
catalytic activity	0.710731808917009	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.352072576393216	bayes_pls_golite062009
methyltransferase activity	0.349480046648587	bayes_pls_golite062009
histone methyltransferase activity	0.34836765632152	bayes_pls_golite062009
protein binding	0.0283208412023089	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: