YRC Public Data Repository - Protein Structure Prediction

Protein:	mtr4
Organism:	Schizosaccharomyces pombe
Length:	1117 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mtr4.

Description	E-value	Query Range	Subject Range
gi\|114600242 - gi\|114600242\|ref\|XP_001145794.1\| PREDICTED: superkiller viralicidic activity 2-like 2 isoform 2 [Pan...	767.0	[0..92]	[1117..38]
SKIV2L2 - superkiller viralicidic activity 2-like 2 (S. cerevisiae)	766.0	[0..92]	[1117..38]
SK2L2_MOUSE - Superkiller viralicidic activity 2-like 2 OS=Mus musculus GN=Skiv2l2 PE=1 SV=1 gi\|71681012 - gi\|71681012\|gb\|AAH99802.1\| RGD1305984 protein [Rattus norvegicus]	765.0	[0..92]	[1117..36]
gi\|114325466 - gi\|114325466\|gb\|AAH28604.3\| Superkiller viralicidic activity 2-like 2 (S. cerevisiae) [Homo sapiens] gi\|61363854 - gi\|61363854\|gb\|AAX42455.1\| KIAA0052 protein [synthetic construct]	764.0	[0..92]	[1117..38]
gi\|149059353, gi... - gi\|77539760\|ref\|NP_001029265.1\| superkiller viralicidic activity 2-like 2 [Rattus norvegicus], gi\|14...	763.0	[0..96]	[1117..42]
gi\|73949523 - gi\|73949523\|ref\|XP_849676.1\| PREDICTED: similar to Superkiller viralicidic activity 2-like 2 isoform...	763.0	[0..92]	[1117..38]

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Predicted Domain #1

Region A:
Residues: [1-97]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGGELDDAF GVFEGKVPKS LKEESKNSQN SQNSQKIKRT LTDKNASNQE QGTKKLESSV  60
   61 GEQESATKRA KIENLKDNQD LIPNNDVNGI HINNSAV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [98-179]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADTKHKPKIG DIAADDISNE VSIKNEGDTI PEATVADSFE QEASLQVAGK VGMTEAKSST  60
   61 EEVVELRHQV RHQVSIPPNY DY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.69897
Match:	1gm5A
Description:	RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [180-722]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPISKHKSPI PPARTYPFTL DPFQAVSIAC IERQESVLVS AHTSAGKTVV AEYAVAQSLR  60
   61 DKQRVIYTSP IKALSNQKYR ELLAEFGDVG LMTGDVTINP DATCLVMTTE ILRSMLYRGS 120
  121 EVMREVAWVI FDEIHYMRDK ERGVVWEETI ILLPDKSHFV FLSATIPNAM QFAEWITKIH 180
  181 RQPCHVVYTD FRPTPLQHYL FPSGSDGIHL VVDEKSNFRE ENFQRAMSAL MEKQGDDPAA 240
  241 MATKGNAKKG KTGKGGVKGP SDIYKIVKMI MVKNYNPVIV FSFSKRECEA LALQMSKLDM 300
  301 NDQTERDLVT TIFNNAVNQL SEKDRELPQI EHILPLLRRG IGIHHSGLLP ILKEVIEILF 360
  361 QEGLLKVLFA TETFSIGLNM PAKTVVFTNV RKFDGKTFRW ISGGEYIQMS GRAGRRGLDD 420
  421 RGIVILMIDE KMDPPVAKSM LKGEADRLDS AFHLSYNMIL NLLRVEGISP EFMLERCFFQ 480
  481 FQNSLEVPKL EAKLEESQQH YDSFTILDER PLEEYHTLKT QLERYRTDVR TVVNHPNFCL 540
  541 SFL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.30103
Match:	1oywA
Description:	Structure of the RecQ Catalytic Core
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [723-795]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGGRLVRVKV GNEDFDWGVV VNVSKRPLPK GQSNEYLPQE SYIVHTLVMV ASDTGPLRIR  60
   61 SGHLPEVHPP AAE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [796-941]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKGKFEVVPF LLSSLDGIAH IRVFLPNDLK SQGQKLTVGK ALSEVKRRFP EGITLLDPVE  60
   61 NMNIKEPTFI KLMKKVNILE SRLLSNPLHN FSELEEKYAE YLRKLALLEE VKDLKKKLSK 120
  121 ARSIMQLDEL NSRKRVLRRL GFTTSD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6

Region A:
Residues: [942-1117]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVIEVKGRVA CEISSGDGLL LTELIFNGMF NDLTPEQCAA LLSCLVFQEK SEVENQRMKE  60
   61 ELAGPLKILQ EMARRIAKVS KESKQELNEE EYVNSFKPSL MEVVYAWAHG ASFAQICKMT 120
  121 DVYEGSLIRM FRRLEELIRQ MVDAAKVIGN TSLQQKMEDT IACIHRDIVF SASLYL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits