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View Structure Prediction Details

Protein: SPAC6B12.04c
Organism: Schizosaccharomyces pombe
Length: 421 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC6B12.04c.

Description E-value Query
Range
Subject
Range
gi|18977625, gi|... - gi|18977625|ref|NP_578982.1| aspartate aminotransferase [Pyrococcus furiosus DSM 3638], gi|18893347|...
329.0 [0..6] [420..1]
gi|57158807, gi|... - gi|57640483|ref|YP_182961.1| aspartate aminotransferase [Thermococcus kodakarensis KOD1], gi|5715880...
325.0 [0..6] [420..1]
AAT_PYRAB - Aspartate aminotransferase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=aspC PE=3 SV=1
AAT_PYRAB - Aspartate aminotransferase OS=Pyrococcus abyssi GN=aspC PE=3 SV=1
324.0 [0..6] [420..1]
gi|166857245, gi... - gi|76795487|ref|ZP_00777860.1| Aminotransferase, class I and II [Thermoanaerobacter ethanolicus ATCC...
gi|241902537, gi... - gi|241902537|ref|ZP_04787270.1| aminotransferase class I and II [Thermoanaerobacter brockii subsp. f...
324.0 [0..1] [420..1]
gi|167038855, gi... - gi|167038855|ref|YP_001661840.1| aminotransferase, class I and II [Thermoanaerobacter sp. X514], gi|...
gi|242231181, gi... - gi|242257293|ref|ZP_04802163.1| aminotransferase class I and II [Thermoanaerobacter sp. X513], gi|24...
322.0 [0..1] [420..1]
gi|7447831, gi|1... - pir||E71009 probable aromatic-amino-acid transaminase (EC 2.6.1.57) PH1371 [similarity] - Pyrococcus...
gi|3257794, gi|1... - gi|3257794|dbj|BAA30477.1| 389aa long hypothetical aspartate aminotransferase [Pyrococcus horikoshii...
320.0 [0..6] [420..1]
gi|169297456, gi... - gi|169344536|ref|ZP_02865505.1| aminotransferase, class I/II [Clostridium perfringens C str. JGS1495...
gi|110683677, gi... - gi|110803176|ref|YP_698027.1| aspartate aminotransferase [Clostridium perfringens SM101], gi|1106836...
319.0 [0..1] [420..1]
gi|18309693, gi|... - gi|18309693|ref|NP_561627.1| aspartate aminotransferase [Clostridium perfringens str. 13], gi|181443...
319.0 [0..1] [420..1]
gi|67916871, gi|... - gi|67916871|ref|ZP_00510560.1| Aminotransferase, class I and II [Clostridium thermocellum ATCC 27405...
gi|196253379, gi... - gi|196253379|ref|ZP_03152009.1| aminotransferase class I and II [Clostridium thermocellum DSM 4150],...
318.0 [0..12] [420..11]
gi|168217160, gi... - gi|182380722|gb|EDT78201.1| aminotransferase, class I/II [Clostridium perfringens NCTC 8239], gi|168...
gi|110674249, gi... - gi|110799602|ref|YP_695159.1| aspartate aminotransferase [Clostridium perfringens ATCC 13124], gi|11...
318.0 [0..1] [420..1]

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Predicted Domain #1
Region A:
Residues: [1-421]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFRGIRPSN KVAASRPDVW TLVNQATAEC KVPPVSLSQG FFNYNPPKFV LDAAKKSIDE  60
   61 VACNQYSHTR GRPSLRKALS EAYSPYFKRT LNPDTEIVVT AGANEGFFSV FAAFLNPGDE 120
  121 VIVMEPFFDQ YISNITMNGG VPVYVPIIPP EEGSVKPVSA GAWKLDMNKL RNAITEKTKM 180
  181 IVINTPHNPL GKIFSEEELN EIADLVLKHN LLVVSDEVYD RLSFVPFVRL ATLRPELFKH 240
  241 VVTVGSGGKT FGCTGWRVGW LIGDESLIKY SAAAHTRICF AVNSPCQEAL AIAFGEAEKH 300
  301 NYYEEYKSSY KKRFEILAKA FDQLEIPYTI PDGSYYTMAN FSKLKLPKDY PFPEEIANRP 360
  361 RDFKLCYWIL KEIGVATIPP TEFYTDEDAP VAENYLRFAF CKTFETLEEA ARRLQKLKDY 420
  421 F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.69897
Match: 1w7lA
Description: Crystal structure of human kynurenine aminotransferase I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
L-aspartate:2-oxoglutarate aminotransferase activity 5.51961002550688 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 1.63055151623667 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 1.63055151623667 bayes_pls_golite062009
transferase activity 1.44093490824786 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
4-aminobutyrate transaminase activity 0.99097016439114 bayes_pls_golite062009
5-aminolevulinate synthase activity 0.54326874956263 bayes_pls_golite062009
binding 0.536634592992536 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.319452731970428 bayes_pls_golite062009
pyridoxal phosphate binding 0.16957228630576 bayes_pls_golite062009
vitamin B6 binding 0.16957228630576 bayes_pls_golite062009
aromatic-amino-acid:2-oxoglutarate aminotransferase activity 0.0916183433120769 bayes_pls_golite062009
cystathionine beta-lyase activity 0.0833010353195099 bayes_pls_golite062009
nucleic acid binding 0.013097682076602 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle