YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC12B10.08c
Organism:	Schizosaccharomyces pombe
Length:	456 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC12B10.08c.

Description	E-value	Query Range	Subject Range
gi\|221312199 - gi\|221312199\|ref\|ZP_03594004.1\| hypothetical protein BsubsN3_00340 [Bacillus subtilis subsp. subtili... gi\|221317132 - gi\|221317132\|ref\|ZP_03598426.1\| hypothetical protein BsubsJ_00340 [Bacillus subtilis subsp. subtilis... gi\|221321395 - gi\|221321395\|ref\|ZP_03602689.1\| hypothetical protein BsubsS_00340 [Bacillus subtilis subsp. subtilis... YACA_BACSU, TILS... - (P37563) Hypothetical UPF0072 protein yacA, tRNA(Ile)-lysidine synthase OS=Bacillus subtilis GN=tilS... TILS_BACSU - tRNA(Ile)-lysidine synthase OS=Bacillus subtilis (strain 168) GN=tilS PE=1 SV=2	281.0	[0..6]	[449..1]
gi\|2127047, gi\|4... - gi\|467456\|dbj\|BAA05302.1\| unknown [Bacillus subtilis], pir\|\|S66097 cell-cycle protein homolog yacA -... gi\|467456\|dbj\|BA... - unknown [Bacillus subtilis]	279.0	[0..9]	[449..18]
TILS_BACCR - tRNA(Ile)-lysidine synthase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 /...	275.0	[0..1]	[441..1]
TILS_BACCZ - tRNA(Ile)-lysidine synthase OS=Bacillus cereus (strain ZK / E33L) GN=tilS PE=3 SV=1	274.0	[0..1]	[441..1]
TILS_BACC1 - tRNA(Ile)-lysidine synthase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=tilS PE=3 SV=1	273.0	[0..1]	[441..1]
gi\|195991035, gi... - gi\|196036405\|ref\|ZP_03103802.1\| tRNA(Ile)-lysidine synthetase [Bacillus cereus W], gi\|195991035\|gb\|E... gi\|225862116, gi... - gi\|225862116\|ref\|YP_002747494.1\| tRNA(Ile)-lysidine synthetase [Bacillus cereus 03BB102], gi\|2257909... TILS_BACHK - tRNA(Ile)-lysidine synthase OS=Bacillus thuringiensis subsp. konkukian GN=tilS PE=3 SV=1 gi\|196047393, gi... - gi\|196047393\|ref\|ZP_03114606.1\| tRNA(Ile)-lysidine synthetase [Bacillus cereus 03BB108], gi\|19602179... gi\|196027396, gi... - gi\|196041776\|ref\|ZP_03109066.1\| tRNA(Ile)-lysidine synthetase [Bacillus cereus NVH0597-99], gi\|19602... TILS_BACHK - tRNA(Ile)-lysidine synthase OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=tilS PE=3 S... gi\|218539357, gi... - gi\|218901265\|ref\|YP_002449099.1\| tRNA(Ile)-lysidine synthetase [Bacillus cereus AH820], gi\|218539357...	273.0	[0..1]	[441..1]
gi\|47570187, gi\|... - gi\|47570187\|ref\|ZP_00240841.1\| cell cycle protein mesJ [Bacillus cereus G9241], gi\|47553131\|gb\|EAL11...	273.0	[0..1]	[441..1]
gi\|49183097, gi\|... - gi\|49183097\|ref\|YP_026349.1\| hypothetical protein BAS0062 [Bacillus anthracis str. Sterne], gi\|49177... gi\|47500464, gi\|... - gi\|47525316\|ref\|YP_016665.1\| hypothetical protein GBAA0062 [Bacillus anthracis str. 'Ames Ancestor']... gi\|30260254, gi\|... - gi\|30260254\|ref\|NP_842631.1\| hypothetical protein BA0062 [Bacillus anthracis str. Ames], gi\|30253575... gi\|229602718, gi... - gi\|229602718\|ref\|YP_002864715.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. A0248], gi\|2... gi\|227812737, gi... - gi\|227812737\|ref\|YP_002812746.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. CDC 684], gi... gi\|254735465 - gi\|254735465\|ref\|ZP_05193173.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. Western North... gi\|254682310 - gi\|254682310\|ref\|ZP_05146171.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. CNEVA-9066] gi\|21398027 - ref\|NP_654012.1\| UPF0021, Uncharacterized protein family UPF0021 [Bacillus anthracis str. A2012] gi\|254756338 - gi\|254756338\|ref\|ZP_05208367.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. Vollum] gi\|254744633 - gi\|254744633\|ref\|ZP_05202312.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. Kruger B] gi\|254762394 - gi\|254762394\|ref\|ZP_05214236.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. Australia 94] gi\|167641508, gi... - gi\|167641508\|ref\|ZP_02399756.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. A0193], gi\|16... gi\|167635086, gi... - gi\|167635086\|ref\|ZP_02393403.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. A0442], gi\|16... gi\|165872559, gi... - gi\|165872559\|ref\|ZP_02217191.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. A0488], gi\|16... gi\|190559937, gi... - gi\|190569013\|ref\|ZP_03021914.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis Tsiankovskii-I], g... gi\|172080036, gi... - gi\|177655625\|ref\|ZP_02936988.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. A0174], gi\|17... gi\|170707562, gi... - gi\|170707562\|ref\|ZP_02898015.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. A0389], gi\|17... TILS_BACAN - tRNA(Ile)-lysidine synthase OS=Bacillus anthracis GN=tilS PE=3 SV=1 gi\|170688892, gi... - gi\|170688892\|ref\|ZP_02880094.1\| tRNA(Ile)-lysidine synthetase [Bacillus anthracis str. A0465], gi\|17...	272.0	[0..1]	[441..1]
gi\|65317524 - gi\|65317524\|ref\|ZP_00390483.1\| COG0037: Predicted ATPase of the PP-loop superfamily implicated in ce...	269.0	[0..1]	[441..5]
gi\|89207184, gi\|... - gi\|89207184\|ref\|ZP_01185730.1\| PP-loop [Bacillus weihenstephanensis KBAB4], gi\|89154864\|gb\|EAR74887....	269.0	[0..1]	[441..1]

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Predicted Domain #1

Region A:
Residues: [1-456]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTIKLKEFY NSLVSIRRRV GHRRLGIAVS GGVDSMLLSW FMKESQIMFG WPNQFIAFVV  60
   61 DHRIRKNSTE EALQTIWNLN RMLIPNVYLN INWGNDDVHS LTNLETIARE HRYQVLTRAC 120
  121 ITHNIRHICT AHHANDQAET IFMRLLRRKP GTWGGLCAMK PVSQIPESDS ICGASNIELL 180
  181 RPLLPYYKNQ ILNTAKQHGI AWEEDPTNAD INLTPRNAIR RFLNQHAALT VEATKLATAF 240
  241 QSLQVNIDNK VDEILKDNIV SYHQPSGTLS LCFSKNELKK HSNLTKEELL LRCLTLTTSC 300
  301 RQIKRSSVVS LCNSVFDGKK LTIAKCLLTS SSIKDDTKLQ LQISRQPFSK AELKKKTITI 360
  361 NPDRYVLWDH RFWIKYSCKN TQTTLILRPL LSKDLNSLKG FLSKEEFLKF CIQVPGHIRF 420
  421 TIPVLSEEND KLVGIPTFGF NFRSDIISNC LHKFKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	67.221849
Match:	1ni5A
Description:	Putative cell cycle protein MesJ, N-terminal domain; Putative cell cycle protein MesJ, middle and C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-oxygen bonds	5.31600041149223	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	5.31600041149223	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	5.31492510480447	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	4.77782949872067	bayes_pls_golite062009
ligase activity	3.71561290487771	bayes_pls_golite062009
catalytic activity	0.828867994386867	bayes_pls_golite062009
DNA binding	0.402138468358303	bayes_pls_golite062009
nucleic acid binding	0.370713117053127	bayes_pls_golite062009
binding	0.322762376257808	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: